Serotonin syndrome is a potentially fatal condition caused by central nervous system serotonergic overactivity. The primary principle of managing serotonin syndrome in pregnancy focuses on discontinuation of offending agents and supportive care. In general, delivery should be avoided pending resolution of serotonin syndrome.
SaraghiMGoldenLHershEV.Anesthetic considerations for patients on antidepressant therapy – Part II. Anesth Prog2018;
65: 60–65.
2.
BoyerEWShannonM.The serotonin syndrome. N Engl J Med2005;
352: 1112–1120.
3.
CunninghamFG. Appendix B: laboratory values in normal pregnancy. In: Protocols for high-risk pregnancies: an evidence-based approach. 5th ed. 2010, pp.587–595.
4.
Gestational hypertension and preeclampsia. Practice Bulletin No. 202American College of Obstetricians and Gynecologists. Obstet Gynecol2019;
133: e1–e25.
5.
Antepartum fetal surveillance.Practice Bulletin No. 145. American College of Obstetricians and Gynecologists. Obstet Gynecol2014;
124: 182–192.
6.
DunkleyEJIsbisterGKSibbrittD, et al.
The Hunter Serotonin Toxicity Criteria; simple and accurate diagnostic decision rules for serotonin toxicity. QJM2003;
96: 639.
7.
2019 USPSTF update.The latest recommendations include 2 topics previously unaddressed: perinatal depression and EKG screening for atrial fibrillation. J Fam Pract2019;
68: 223–228.
8.
ACOG Committee Opinion No. 354:
Treatment with selective serotonin reuptake inhibitors during pregnancy. Obstet Gynecol2006;
108: 1601–1603.
9.
ACOG Practice Bulletin No. 87 November 2007: Use of psychiatric medications during pregnancy and lactation. Obstetric Gynecology 2007; 110 (5): 1179.
10.
Frise CJ, Mackillop L, Williamson C, et al. Starvation ketoacidos in pregnancy. European Journal of Obstetrics & Genecology and Reproductive Biology 2013; 167: 1–7.
11.
Teff KL, Rickels MR, Rickels K, et al. Antipsychotic-induced insulin resistance and postprandial hormonal dysregulation independent of weight gain or psychiatric disease. Diabetes 2013; 62: 3232–3240.