Hyperemesis gravidarum is a complication of pregnancy associated with severe nausea and vomiting that can lead to fluid-electrolyte imbalances and nutritional deficiencies. Wernicke’s encephalopathy is a neurologic manifestation of acute thiamine (vitamin B1) deficiency. We describe a case of hyperemesis gravidarum presenting with gait ataxia and nystagmus which led to a diagnosis of Wernicke’s encephalopathy.
WegrzyniakLJRepkeJTUralSH.Treatment of hyperemesis gravidarum. Rev Obstet Gynecol2012;
5: 78–84.
4.
ThomsonADGuerriniIMarshallEJ.The evolution and treatment of Korsakoff’s syndrome: out of sight, out of mind?Neuropsychol Rev2012;
22: 81–92.
5.
ShehmarMMcCleanMANelson-PiercyC, et al.The management of nausea and vomiting of pregnancy and hyperemesis gravidarum.
UK:
Royal College of Obstetricians and Gynecologists, 2016, pp.1–27.
6.
DoddsLFellDBJosephKS, et al.
Outcomes of pregnancies complicated by hyperemesis gravidarum. Obstet Gynecol2006;
107: 285–292.
7.
KoudijsHMSavitriAIBrowneJL, et al.
Hyperemesis gravidarum and placental dysfunction disorders. BMC Pregnancy Childbirth2016;
16: 374.
8.
VandraasKVikanesÅVangenS, et al.
Hyperemesis gravidarum and birth outcomes – a population-based cohort study of 2.2 million births in the Norwegian Birth Registry. BJOG2013;
120: 1654–1660.
9.
MartinPRSingletonCKHiller-SturmhofelS.The role of thiamine deficiency in alcoholic brain disease. Alcohol Res2003;
134–142.
10.
AshrafVPrijeshJPraveenkumarR, et al.
Wernicke’s encephalopathy due to hyperemesis gravidarum: clinical and magnetic resonance imaging characteristics. J Postgrad Med2016;
62: 260–263.
11.
ChiossiGNeriICavazzutiM, et al.
Hyperemesis gravidarum complicated by Wernicke encephalopathy: background, case report, and review of the literature. Obstet Gynecol Surv2006;
61: 255–268.
12.
ManzoGGennaroADCozzolinoA, et al.
MR imaging findings in alcoholic and nonalcoholic acute Wernicke’s encephalopathy: a review. BioMed Res Int2014;
2014: 1–12.