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Abstract

Background:

The national pharmacovigilance (PV) system has been established in many countries worldwide following the thalidomide tragedy. Nurses have an important role in recognising and reporting any Adverse Drug Reaction (ADR); however, their role has not been widely explored, particularly in Southeast Asian countries.

Aims:

To assess the knowledge, attitudes and practice (KAP) about PV activities, along with barriers and facilitators that affect ADR reporting among hospital nurses in Malaysia. The present study also explores the relationship between demographic characteristics and predictors of KAP among hospital nurses in Malaysia.

Methods:

A multicentre, questionnaire-based, cross-sectional study was conducted in March–May 2021, among nurses working at tertiary care hospitals in Malaysia.

Results:

The mean KAP score of study participants was 57 ± 11. Overall participants had poor ADR knowledge (37.4%), and poor reporting practices (48.9%). Age >30 years (AOR = 2.7 (1.13–6.8), p = 0.02), and working experience of greater than 10 years (AOR = 2.44 (1.08–5.52), p = 0.03), were significantly associated with good ADR knowledge and reporting practices among study participants.

Conclusions:

In summary, study findings offer valuable insight for developing targeted interventions and formal training to improve nurses’ ADR knowledge and reporting practices. Addressing gaps in these areas can enhance patient safety and overall healthcare quality.

Keywords

adverse drug reaction barriers facilitators Malaysia medication safety pharmacovigilance

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Knowledge,attitude and practices about pharmacovigilance activities among hospital nurses: a multicentre cross-sectional survey