Spasticity is commonly defined as a velocity-dependent increase in tonic stretch re flexes that results from a variety of disorders affecting the brain and spinal cord. Treat ment of spasticity is generally considered when the increase in tone interferes with functional activities, such as positioning, mobility, or daily cares, when it is painful, or when it leads to complications such as contractures or skin breakdown. This re view discusses the pathophysiology of spasticity and details the various treatments avail able, including physical and occupational therapy modalities, use of splints and or thoses, oral and intrathecal medications, nerve blocks, botulinum toxin injections, and orthopedic and neurosurgical interventions.
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