This study reports the case of an HIV-infected patient with disseminated tuberculosis who presented an immune reconstitution inflammatory syndrome (IRIS) revealed by an acute kidney disease 45 and 15 days after initiation of antituberculosis therapy and HAART, respectively. Prednisone therapy and the transient withdrawal of HAART improved the renal function and the clinical condition of this patient. All published case reports of IRIS revealed by acute renal failure in HIV-infected patients are also reviewed.
French MA, Lenzo N., John M., et al. Immune restoration disease after the treatment of immunodeficient HIV-infected patients with highly active antiretroviral therapy. HIV Med. 2000;1:107-115.
2.
Jehle AW, Khanna N., Sigle JPAcute renal failure on immune reconstitution in an HIV-positive patient with miliary tuberculosis. Clin Infect Dis. 2004 ;38:e32-e35.
3.
Daugas E., Plaisier E., Boffa JJ, et al. Acute renal failure associated with immune restoration inflammatory syndrome. Nat Clin Pract Nephrol. 2006;2:594-598.
4.
Izzedine H., Brocheriou I., Martinez V., Deray G.Immune reconstitution inflammatory syndrome and acute granulomatous interstitial nephritis. AIDS. 2007;21:534-535.
5.
Shelburne SA , Visnegarwala F., Darcourt J., et al. Incidence and risk factors for immune reconstitution inflammatory syndrome during highly active antiretroviral therapy . AIDS. 2005;19:399-406.
