Sage Journals: Discover world-class research

Abstract

Purpose:

To compare the efficacy of thrombolysis with and without predilation of the inferior vena cava (IVC) for Budd–Chiari syndrome (BCS) with old IVC thrombosis.

Methods:

We divided 40 patients with BCS with old IVC thrombosis into 2 groups, group A (n = 21), thrombolysis after dilation of the obstructed IVC and group B (n = 19), thrombolysis without predilation of the obstructed IVC. Thrombolysis was performed via urokinase administration through the dorsal vein of the foot.

Results:

Color Doppler ultrasonography at 30 days showed complete resolution of the thrombus in 21 (100%) group A patients and 6 group B patients (31.6%; P < .001). Thrombolysis was achieved using a lower dose of urokinase and within a shorter time frame in group A than in group B (P < .001).

Conclusions:

Thrombolysis after dilation was superior to thrombolysis alone and was safe and efficacious in patients with BCS with old IVC thrombosis.

Keywords

Budd–Chiari syndrome inferior vena cava thrombus thrombolysis

Get full access to this article

View all access options for this article.

References

Janssen

Garcia-Pagan

Elias

Mentha

Hadengue

Valla

. Budd-Chiari syndrome: a review by an expert panel. J Hepatol. 2003;38(3):364–371.

Ludwig

Hashimoto

McGill

van Heerden

. Classification of hepatic venous outflow obstruction: ambiguous terminology of the Budd-Chiari syndrome. Mayo Clin Proc. 1990;65(1):51–55.

Lee

Villavicencio

Kim

. Primary Budd-Chiari syndrome: outcome of endovascular management for suprahepatic venous obstruction. J Vasc Surg. 2006;43(1):101–108.

Wang

Xiao

. Percutaneous balloon angioplasty of inferior vena cava in Budd-Chiari syndrome-R1. Int J Cardiol. 2002;83(2):175–178.

Feng

Zhong

. Clinical application of interventional techniques in the treatment of Budd-Chiari syndrome. Chin Med J (Engl). 2003;116(4):609–615.

Ding

Han

Shui

Wang

. Treatment of Budd-Chiari syndrome with urokinase following predilation in patients with old inferior vena cava thrombosis. Radiol Med. 2011;116(1):56–60.

Wang

Ding

Han

Comparative study of predilation with stent filter for Budd-Chiari syndrome with old IVC thrombosis: A nonrandomized prospective trial. Eur J Radiol. 2012;81(6):1158–1164.

Ding

Han

Shui

Wang

. Budd-Chiari syndrome with fresh inferior vena cava thrombosis: agitation thrombolysis and balloon dilation. Vasa. 2011;40(1):57–63.

Garcia-Pagán

Heydtmann

Raffa

. TIPS for Budd-Chiari syndrome: long-term results and prognostics factors in 124 patients. Gastroenterology. 2008;135(3):808–815.

10.

Qiao

Liu

Chen

Zhang

. Interventional endovascular treatment for Budd-Chiari syndrome with long-term follow-up. Swiss Med Wkly. 2005;135(21-22):318–326.

11.

Zhang

. Long-term effect of stent placement in 115 patients with Budd-Chiari syndrome. World J Gastroenterol. 2003;9(11):2587–2591.

12.

Corso

Intotero

Solcia

Castoldi

Rampoldi

. Treatment of Budd-Chiari syndrome with transjugular intrahepatic portosystemic shunt (TIPS). Radiol Med (Italy). 2008;113(5):727–738.

13.

Darwish Murad

Plessier

Hernandez-Guerra

. Collaborators (99) Etiology, management, and outcome of the Budd-Chiari syndrome. Ann Intern Med. 2009;151(3):167–175.

14.

Han

Ding

. Retrieval stent filter: treatment of Budd Chiari syndrome complicated with inferior vena cava thrombosis--initial clinical experience. Ann Thorac Surg. 2007;83(2):655–660.

15.

Ding

Han

Shui

Wang

. Outcome of a retrieval stent filter and 30 mm balloon dilator for patients with Budd-Chiari syndrome and chronic inferior vena cava thrombosis: a prospective pilot study. Clin Radiol. 2010;65(8):629–635.

Outcomes of Thrombolysis With and Without Predilation of the Inferior Vena Cava (IVC) in Patients With Budd–Chiari Syndrome With Old IVC Thrombosis

Abstract

Purpose:

Methods:

Results:

Conclusions:

Keywords

Get full access to this article

References