Abstract
Background:
Spinal cord involvement in Behçet’s disease is not well studied.
Objective:
To evaluate the clinical, laboratory and magnetic resonance imaging characteristics of spinal cord involvement in Behçet’s disease.
Methods:
We retrospectively reviewed 10 spinal cord involvements in seven patients with Behçet’s disease.
Results:
The median age of onset for spinal cord involvement was 32 (23–45 years). Two patients showed a secondary progressive course. Cerebrospinal fluid findings revealed mild to moderate pleocytosis and/or elevated protein levels. In eight spinal cord involvements, the lesion was longer than three vertebrae. Serum anti-aquaporin-4 antibody was negative in all four patients tested.
Conclusions:
Longitudinally extensive transverse myelitis is a characteristic manifestation of spinal cord involvement in Behçet’s disease.
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