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Abstract

French

The literature on glaucoma and/or cataracts associated with various types of clinically used drugs and certain chemicals has been surveyed. The physicochemical and pharmacological bases of these ocular toxicities have been critically analyzed wherever possible. Various means of avoiding or preventing these processes have also been reviewed. It is hoped that awareness and better understanding of drug-induced ocular toxicities may prevent or minimize damage to this very intricate and sensitive organ of the body.

Keywords

glaucoma cataract structure-side effect sorting adverse reactions

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References

Caspar

. Zur Kenntnis der gewerblichen Augenschadigungen durch Naphthalin. Klin Monatsbl Angenheilkd 1917; 59: 142.

Horner

Jones

Boardman

. Cataracts following the use of dinitrophenol. JAMA 1935; 105: 108.

Boardman

. Rapidly developing cataract after dinitrophenol. JAMA 1935; 105: 108.

Cogan

. Dinitrophenol cataract. JAMA 1935; 105: 793.

Lazar

. Cataract following the use of dinitrophenol. JAMA 1935; 105: 794.

Kniskern

. Cataracts following dinitrophenol. JAMA 1935; 105: 794.

Allen

Benson

. Late development of cataract following use of dinitrophenol about a year before. JAMA 1935; 105: 795.

Shutes

. Dinitrophenol. Am J Ophthalmol 1935; 18: 752.

Whalman

. Dinitrophenol cataract. Am J Ophthalmol 1936; 19: 885–8.

10.

Lien

Gudauskas

. Structure-side effect sorting of drugs. I. Extrapyramidal syndrome. J Pharm Sci 1973; 62: 645–7.

11.

Lien

Gudauskas

. Structure-side effect sorting of drugs. II. Skin sensitization. J Pharm Sci 1973; 62: 1968–71.

12.

Lien

. Adverse reactions and chemical structure. In: Bungaard

Juul

Kofod

, eds. Alfred Benzon symposium X. Drug design and adverse reactions. Copenhagen: Munksgaard, 1977: 233–45.

13.

Lien

. Structure-side effect sorting of drugs. III. Hepatotoxicities. Calif Pharmacist 1978; 26: 34–44.

14.

Lien

. Structure-side effect sorting of drugs. IV. Nephrotoxicities. J Clin Hosp Pharm 1980; 5: 225–50.

15.

Meyler

Herxheimer

. Side effects of drugs. Vol. VI. Amsterdam: Excerpta Medica, 1968.

16.

Meyler

Herxheimer

. Side effects of drugs. Vol. VII. Amsterdam: Excerpta Medica, 1972.

17.

Dukes

MNG

, ed. Meyler's side effects of drugs. Vol. VIII. Amsterdam: Excerpta Medica, 1975.

18.

Dukes

MNG

, ed. Side effects of drugs annual 1. Amsterdam: Excerpta Medica, 1977.

19.

Dukes

MNG

, ed. Side effects of drugs annual 2. Amsterdam: Excerpta Medica, 1978.

20.

Dukes

MNG

, ed. Side effects of drugs annual 3. Amsterdam: Excerpta Medica, 1979.

21.

AMA drug evaluations. 1st ed. Chicago: American Medical Association, 1971.

22.

Meyler

Peck

, eds. Drug induced diseases. Vol. 3. Amsterdam: Excerpta Medica, 1968.

23.

Meyler

Peck

, eds. Drug induced diseases. Vol. 4. Amsterdam: Excerpta Medica, 1972.

24.

Davies

, ed. Textbook of adverse drug reactions. Oxford: Oxford University Press, 1977.

25.

Hollwich

Boateng

Kolck

. In: Bellow

, ed. Cataract and abnormalities of the lens. New York: Grime and Stratton, 1975.

26.

Berliner

. Cataract following inhalation of para-dichlorobenzene vapor. Arch Ophthalmol 1939; 22: 1023.

27.

Cluff

Caranasos

Stewart

, eds. Clinical problems with drugs. Philadelphia: Saunders, 1975.

28.

Casarett

Doull

, eds. Toxicology. New York: Macmillan, 1975.

29.

Fraunfelder

. Drug-induced ocular side effects and drug interactions. Philadelphia: Lea and Febiger, 1976.

30.

Von Sallmann

Grimes

Collins

. Mimosine cataract. Am J Ophthalmol 1959; 47: 107–17.

31.

AMA Drug Evaluations, 4th ed. Chicago: American Medical Association, 1980.

32.

Bron

. Mechanisms of ocular toxicity. In: Gorrod

. Drug toxicity. London: Taylor and Francis, 1979: 229–53.

33.

Heydenreich

. Chemische-toxische Schäden der Augen. Klin Monatsbl Augenheilkd 1966; 149: 145.

34.

Salmony

. Some biochemical changes in naphthalene cataract. Br J Ophthalmol 1960; 44: 29–34.

35.

Hanison

. Bilateral lens opacities associated with the use of di-isopropyl fluorophosphate eyedrops. Am J Ophthalmol 1960; 50: 153–4.

36.

Becker

. Cataracts and topical corticosteroids. Am J Ophthalmol 1964; 58: 872–3.

37.

Axelsson

Holmberg

. The frequency of cataract after miotic therapy. Acta Ophthalmol 1966; 44: 421–8.

38.

De Roetth

. Lens opacities in glaucoma patients on phospholine iodide therapy. Am J Ophthalmol 1966; 62: 619–28.

39.

Shaffer

Hetherington

. Anticholinesterase drugs and cataracts. Am J Ophthalmol 1966; 62: 613–8.

40.

De Roetth

. Lenticular opacities in glaucoma patients receiving echothiophate iodide therapy. JAMA 1966; 195: 664–6.

41.

De Long

. Incidence and significance of chlorpromazine-induced eye changes. Dis Nerv Sys 1965; 29: 19–22.

42.

Baer

Harber

. Photosensitivity induced by drugs. JAMA 1965; 192: 989–90.

43.

Slansky

Kolbert

Gartner

. Exophthalmos induced by steroids. Arch Ophthalmol 1967; 77: 579–81.

44.

Michon

Kimoshita

. Experimental miotic cataract II: Permeability, cation transport, and intermediary metabolism. Arch Ophthalmol 1968; 79: 611–6.

45.

Laties

. Localization in cornea and lens of topically-applied irreversible Cholinesterase inhibitors. Am J Ophthalmol 1969; 68: 848–57.

46.

Chizek

Franceschetti

. Oral contraceptives: Their side effects and ophthalmological manifestations. Surv Ophthalmol 1969; 14: 90–105.

47.

Hollwich

Verbeck

. Side-effects of oral contraceptives on the eye. Ger Med Mth 1970; 15: 155–9.

48.

Stempel

. Drug-induced photosensitivity. J Am Pharm Assoc 1973; NS13: 200–4.

49.

Smith

. Handbook of ocular toxicity. Acton, MA: Publishers Science Group, 1976.

50.

Weinstock

Scott

. Effects of various agents on drug-induced opacities of the lens. Exp Eye Res 1967; 6: 368–75.

51.

Reid

Blouin

Schermer

. A review of psychotropic medications and the glaucomas, hit Pharmacopsychiatry 1976; 11: 163–76.

52.

Suden

. Opacities of the lens induced by adrenalin in the mouse. Am J Physiol 1940; 130: 543–8.

53.

Suden

Wyman

. Adrenalin-induced opacities of the lens in the rat. Endocrinology 1940; 27: 628–32.

54.

Weinstock

Stewart

Butterworth

. Lenticular effect in mice of some morphine-like drugs. Nature 1958; 182: 1519–20.

55.

Grant

. Toxicology of the eye, 2nd ed. Springfield, IL: CC Thomas, 1974.

56.

Lezenius

. Ein Fall von Naphthalm Katarakt am Meerscheinchen. Klin Monatsbl Augenheilkd 1902; 40: 129.

57.

Ghetti

Mariani

. Augenveränderungen durch Naphthalin. Ber Dtsch Ophthalmol Ges 1957: 299–300.

58.

D'Arcy

Griffin

. Iatrogenic disease. London: Oxford University Press, 1972.

59.

Davidson

. Reports of ocular adverse reactions. Trans Ophthalmol Soc 1973; 93: 495–510.

60.

Oppelt

White

Halpert

. The effect of corticosteroids on aqueous humor formation rate and outflow facility. Invest Ophthalmol 1969; 8: 535–41.

61.

Armaly

. Inheritance of dexamethasone hypertension and glaucoma. Arch Ophthalmol 1967; 77: 747–51.

62.

Bedrossian

Eriken

. The treatment of ocular inflammation with medrysone. Arch Ophthalmol 1969; 81: 184–91.

63.

FDA drug bulletin. Food and Drug Administration. Department of Health and Human Services, Rockville, MD, 1980; 10 (No. 2).

64.

Weinstock

Stewart

. Occurrence in rodents of reversible drug-induced opacities of the lens. Br J Ophthalmol 1961; 45: 408–14.

65.

Weinstock

. Similarity between receptors responsible for the production of analgesia and lenticular opacity. Br J Pharmacol 1961; 17: 433–41.

66.

Weinstock

Marshall

. The influence of the sympathetic nervous system on the action of drugs on the lens. J Pharmacol Exp Ther 1969; 166: 8–13.

67.

Faust

. Hormonal contraception: Ophthalmologic investigation. EENT Digest 1968; 30: 62–6.

68.

Varma

Kinoshita

. Inhibition of lens aldose reductase by flavonoids — Their possible role in the prevention of diabetic cataracts. Biochem Pharmacol 1976; 25: 2502–13.

69.

Segelman

Varma

Wagner

Seligmann

. Cannabis saliva L. (marijuana)IX: Lens aldose reductase inhibitory activity of marijuana flavone C-glycosides. J Pharm Sci 1977; 66: 1358–9.

70.

Varma

Schocket

Richards

. Implications of aldose reductase in cataracts in human diabetes. Invest Ophthalmol Vis Sci 1978; 18: 237–41.

71.

Varma

Mikuni

Kinoshita

. Flavonoids as inhibitors of lens aldose reductase. Science 1975; 188: 1215–6.

Structure-Side Effect Sorting of Drugs: V. Glaucoma and Cataracts Associated with Drugs and Chemicals

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