Ovarian hyperstimulation syndrome (OHSS) is a rare iatrogenic complication of ovarian stimulation. Thromboembolic events are the most feared complication of OHSS. Most of the thrombotic events (75%) are of the venous origin. Stroke represents a rare but life-threatening complication of severe OHSS. A 29-year old woman was admitted to our emergency room, with left sided weakness, difficulty in breathing and nausea. The patient was given the diagnosis of OHSS and right middle cerebral artery infarction. Here we emphasise that the development of ovulation induction is a newly recognised cause of cerebral stroke in an otherwise healthy woman.
BartkovaA., SanakD., DostalJ., HerzigR., OtrubaP., VlachovaI.Acute ischaemic stroke in pregnancy: a severe complication of ovarian hyperstimulation syndrome. Neurol Sci2008; 29(6): 463–6.
4.
SongT.J., LeeS.Y., OhS.H., LeeK.Y.Multiple cerebral infarctions associated with polycystic ovaries and ovarian hyperstimulation syndrome. Eur Neurol2008; 59(1-2): 76–8.
5.
ChanW.S.The ‘ART’ of thrombosis: a review of arterial and venous thrombosis in assisted reproductive technology. Curr Opin Obstet Gynecol2009; 21(3): 207–18.
6.
SerourG.I., AboulgharM., MansourR., SattarM.A., AminY., AboulgharH.Complications of medically assisted conception in 3,500 cycles. Fertil Steril1998; 70(4): 638–42.
7.
De KeyserJ., GdovinováZ., UyttenboogaartM., VroomenP.C., LuijckxG.J.Intravenous alteplase for stroke: beyond the guidelines and in particular clinical situations. Stroke2007; 38(9): 2612–8.
