A patient with biopsy-diagnosed polyarteritis nodosa showed central nervous system (CNS) involvement and evidence of intrathecal synthesis of immunoglobulins, coincident with very high serum levels of anticardiolipin antibodies (aCL). Cerebral angiography was normal. We suggest that aCL could be directly implicated in the CNS damage.
Moore PM, Cupps TRNeurological complications of vasculitis. Ann Neurol1983; 14: 155-67.
2.
Lightfoot RW Jr, Michel BA, Bloch DA et al. The American College of Rheumatology 1990 criteria for the classification of polyarteritis nodosa. Arthritis Rheum1990; 33: 1088-93.
3.
Agopian MS, Boctor FN, Peter JBFalse positive result for IgM anticardiolipin antibody due to IgM rheumatoid factor. Arthritis Rheum1988; 31: 1212-13.
4.
Briley DP, Coull BM, Goodnight SH Jr. Neurological disease associated with antiphospholipid antibodies . Ann Neurol1989; 25: 221-7.
5.
Lie JTVasculopathy in the antiphospholipid syndrome: thrombosis or vasculitis, or both? J Rheumatol1989; 16: 713-15.
