Endocarditis and ulnar artery aneurysm as presenting features of antiphospholipid syndrome and polyarteritis nodosa

Abstract

Antiphospholipid syndrome in association with vasculitis is highlighted in this report. The combination of thrombotic and inflammatory processes resulted in endocarditis, aneurysm formation and thrombosis. To our knowledge this is the first presentation of a large vessel aneurysm in these conditions. Anticoagulation and immunosuppression are the treatment modalities of choice.

Keywords

aneurysm antiphospholipid syndrome endocarditis polyarteritis nodosa

Get full access to this article

View all access options for this article.

References

Castellino G , Khamashta MA , Hughes GRV. The antiphospholipid syndrome . Eur J Intern Med 1999; 10: 191-197 .

Hughes GRV. The antiphospholipid syndrome: ten years on . Lancet 1993; 342: 341-344 .

Alarcon-Segovia D , Drenkard C. Vasculitis and the antiphospholipid syndrome . Rheumatol (Oxford) 2000; 39: 922-923 .

Dasgupta B , Almond MK , Tanqueray A. Polyarteritis nodosa and the antiphospholipid syndrome . Br J Rheumatol 1997; 36: 1210-1212 .

Norden DK , Ostrov BE , Shafritz AB , Von Feldt JM. Vasculitis associated with antiphospholipid syndrome . Semin Arthritis Rheum 1995; 24: 273-281 .

Lightfoot RW , Michel BA , Bloch DA. The American College of Rheumatology 1990 criteria for the classification of polyarteritis nodosa . Arthritis Rheum 1990; 33: 1088-1093 .

Wilson WA , Gharavi AE , Koike T et al. International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: report of an international workshop . Arthritis Rheum 1999; 42: 1309-1311 .

Malaviya AN. Antiphospholipid (Hughes) syndrome: a review with update . APLAR J Rheumatol 2003; 6: 160-169 .

Matteson EL. A history of early investigation in polyarteritis nodosa . Arthritis Care Res 1999; 12: 294-302 .

10.

Stone JH. Polyarteritis nodosa . JAMA 2002; 288: 1632-1639 .

11.

Travers RL , Allison DJ , Brettle RP , Hughes GRV. Polyarteritis nodosa: a clinical and angiographic analysis of 17 cases . Semin Arthritis Rheum 1979; 8: 184-199 .

12.

Dongola NA , Foord KD. Angiographic features associated with antiphospholipid syndrome . Br J Radiol 2000; 73: 1215-1218 .

13.

Hagspiel KD , Angle JF , Spinosa DJ , Matsumoto AH. Polyarteritis nodosa-systemic necrotizing vasculitis with involvement of hepatic and superior and mesenteric arteries . Radiology 1999; 212: 359-364 .