The development of a small diameter (≤5 mm) arterial prosthesis requires the appropriate selection of materials, structure and fabrication method so as to provide adequate mechanical properties, superior biocompatibility and precise control over the diameter. In this study, 100% polyester, 100% silk fibroin and a combination of both yarns were woven into seamless tubular prototype prostheses with different basic weaves. After degumming/scouring they met a target inner diameter of 3.9±0.3 mm which demonstrates that weaving is a precise way to manufacture small caliber arterial prostheses. In conclusion, the bicomponent polyester/silk woven samples had superior mechanical properties and improved cytocompatibility compared to commercial ePTFE devices.
MogheAKGuptaBS. Small-diameter blood vessels by weaving: prototyping and modeling. J Text Inst2008; 99: 467–477.
3.
MotlaghDYangJLuiKY. Hemocompatibility evaluation of poly(glycerol-sebacate) in vitro for vascular tissue engineering. Biomaterials2006; 27: 4315–4324.
4.
BérardXRémy-ZolghadriaMBourget Ch. Capability of human umbilical cord blood progenitor-derived endothelial cells to form an efficient lining on a polyester vascular graft in vitro. Acta Biomater2009; 5: 1147–1157.
5.
BonzonNLefebvreFFerreN. New bioactivation mode for vascular prostheses made of Dacron polyester. Biomaterials1995; 16: 747–751.
Vepari ChKaplanDL. Silk as a biomaterial. Prog Polym Sci2007; 32: 991–1007.
8.
EnomotoSSumiMKajimotoK. Long-term patency of small-diameter vascular graft made from fibroin, a silk-based biodegradable material. J Vasc Surg2010; 51: 155–157.
9.
FreddiGMossottiRInnocentiR. Degumming of silk fabric with several proteases. J Biotechnol2003; 106: 101–112.
10.
PitarresiGPalumboFSFioricaC. Electrospinning of a,b-poly(N-2-hydroxyethyl)-DL-aspartamidegraft- polylactic acid to produce a fibrillar scaffold. Eur Polym J2010; 46: 181–184.
11.
HuangCGengXHKeQF. Preparation of composite tubular grafts for vascular repair via electrospinning. Progr Nat Sci: Mater Int2012; 22(2): 108–114.
12.
SatoMNakazawaYTakahashiR. Small-diameter vascular grafts of bombyx mori silk fibroin prepared by a combination of electrospinning and sponge coating. Mater Lett2010; 64: 1786–1788.
13.
ZhouJCaoCBMaXL. A novel three-dimensional tubular scaffold prepared from silk fibroin by electrospinning. Int J Biol Macromol2009; 45: 504–510.
14.
AhmedMGhanbariHCousinsBG. Small calibre polyhedral oligomeric silsesquioxane nanocomposite cardiovascular grafts: influence of porosity on the structure, haemocompatibility and mechanical properties. Acta Biomater2011; 7: 3857–3867.
15.
Ji XP. The analysis of wall structure and properties of small diameter ePTFE vascular prosthesis. Master Thesis, Donghua University, 2011.
16.
International Organization for Standardization. Cardiovascular implants - Tubular vascular prostheses. ISO 7198, Geneva, Switzerland: International Organization for Standardization, 1998, pp. 11–25.
17.
GuidoinRKingMWMarceauD. Textile arterial prostheses: is water permeability equivalent to porosity?J Biomed Mater Res1987; 21: 65–87.
18.
BauerATStrozykEAGorzelannyC. Cytotoxicity of silica nanoparticles through exocytosis of von Willebrand factor and necrotic cell death in primary human endothelial cells. Biomaterials2011; 32: 8385–8393.
KonigGMcAllisterTNDusserreN. Mechanical properties of completely autologous human tissue engineered blood vessels compared to human saphenous vein and mammary artery. Biomaterials2009; 30: 1542–1550.
21.
Shen GT, Lin J, Zhang HQ, et al. Comparison of the radial compliance of three kinds of vascular prostheses and pig’s carotid based on dynamic-simulated condition. In: IFMBE Proceedings of World Congress on Medical Physics and Biomedical Engineering, Beijing, China, 2012, pp. 176–179.
