Equations were developed to predict the time required before a toxic effect is observed in a living body exposed to air containing a toxic gas or a mixture of toxic gases. Values for the constants in the equations for CO and HCN were calculated from data on animal experiments found in literature. The predicted times were compared with times from experiments where the concentration of toxic gases was varied with time.
Tsuchiya, Y. and Nakaya, I., "Numerical Analysis of Fire Gas Toxicity: Single and Multiple-Component Systems," 4th expert meeting of the Canada-Japan-USA cooperative study on fire gas toxicity, Tsukuba, JapanProceedings in print (May 15-16, 1985).
2.
Sakurai, T., "Toxic Gas Test by the Several Pure and the Mixture Gas,"presented at the 3rd expert meeting of the Canada-Japan-USA cooperative study on fire gas toxicity, Ottawa, Canada (October 23-25, 1984).
3.
Hartzell, G.E. , Priest, D.N. and Switzer, W.G., "Mathematical Modeling of Intoxication of Rats by CO and HCN,"J. Fire Sciences , Vol. 3, p. 115 (1985).
4.
Kaplan, H.L. and Hartzell, G.E., "Modeling of Toxicological Effects of Fire Gases,"J. Fire Sciences, Vol. 2, p. 286 (1984).
5.
Hartzell, G.E. , Packham, S.C. and Switzer, W.G., "Assessment of Toxic Hazards of Smoke: Toxicological Potency and Intoxication Rate Thresholds,"Fire and Materials, Vol. 7, p. 128 (1983).
6.
Hartzell, G.E., Packham, S.C., Hileman, F.D., Islael, S.C., Dickman, M.L., Baldwin, R.C. and Micelson, R.W., "Physiological and Behavioral Responses to Fire Combustion Products,"4th Intl. Cellular Plastics Conference, SPI Canada, Montreal, Canada (Nov. 18, 1976).
7.
Minchin, L.T. , "Mild Carbon Monoxide Poisoning as an Industrial Hazard,"Industrial Chemist, Vol. 30, p. 381 (1954).
