Five hemodialysis patients were treated with combined hemodialysis-hemoperfusion with their conventional hemodialyzer plus a 70-gram ultrathin collodion coated activated charcoal device for a total of 63 months. Indications for this therapy included pericarditis, peripheral neuropathy, clotting of conventional hemodialyzers and reduction of dialysis time and frequency. The outcome was beneficial in all cases and stable biochemical and hematological parameters were maintained. No increase in heparin requirements was noted and the therapy was thought to be cost-effective.
ChangT.M.S., ChiritoE., BarréP.E., ColeC., HewishM.Clinical performance characteristics of a new combined system for simultaneous hemoperfusion hemodialysis-ultrafiltration in series.Trans Amer Soc Artif Int Organ1975; 21: 502–9.
2.
ChangT.M.S., GondaA., DirksJ.H., CoffeyJ.F., Lee-BurnsT.ACAC microcapsules artificial kidney for the long-term and short term management of eleven patients with chronic renal failure.Tran Am Soc Artif Int Organs1972; 18: 465–72.
3.
StefoniS., ColiL., FeliciangeliG., BaldratiL., BonominiV.Regular hemoperfusion in regular dialysis treatment. A long-term study.Int J Artif Organs1980; 3: 348–53.
4.
StefoniS., FeliciangeliL., ColiR., PrandiniR., BonominiV.Use of combined hemodialysis/hemoperfusion in chronic uremia.Contr Nephrol1982; 29: 123–32.
5.
OdakaM., TabataY., KobayashiH., NomuraY., SomaH., HirasawaH., SatoH.Clinical experience of bead-shaped charcoal haemoperfusion in chronic renal failure and fulminant hepatic failure; in Chang, eds Artificial kidney, artificial livers, and artificial cells.Plenum Press, New York, 79–88, 1978.
6.
MartinA.M., GibbinsT.K., KimmitT., RennieF.Hemodialysis and hemoperfusion in the treatment of uremic pericarditis. A study of 13 cases.Dial Transplant1979; 8: 135.
7.
OdakaM., HirasawaH., KobayashiH.Clinical and fundamental studies of cellulose coated bead-shaped charcoal haemoperfusion; in SidemanChang, eds Hemoperfusion: kidney and liver support and detoxification. Part I, Hemisphere, Washington, 45–55, 1980.
8.
AgishiT., YamashitaN., OtaR.Clinical results of direct charcoal hemoperfusion for endogenous and exogenous intoxication; in SidemanChang, eds Hemoperfusion: Kidney and liver support and detoxification. Part I, Hemisphere, Washington, 255–63, 1980.
9.
OtsubaO., KuzuharaK., SimadaY.Treatment of uremic peripheral neuritis by direct haemoperfusion with activated charcoal.Proc Eur Dial Transpl Ass1979; 16: 731–6.
10.
ChangT.M.S., BarréP.E.Effect of desferrioxamine on removal of aluminium and iron by coated charcoal haemoperfusion and hemodialysis.Lancet1983; 2: 1051–3.
11.
ChangT.M.S., BarréP.E., KuruvillaS., MessierD., ManN., RessurreccionE.Phase one clinical trial of a new composite artificial kidney: A single unit combining dialysis with hemoperfusion.Trans Am Soc Artif Organs1982; 28: 43–8.
12.
ChangT.M.S.Assessment of clinical trials of charcoal hemoperfusion in uremic patients.Clin Nephrol1979; 11: 111–9.
13.
ChangT.M.S.Artificial cells in hemoperfusion and other applications.Nephron1984; 36: 161–8.
14.
ChangT.M.S., BarréP.E., KuruvillaS.Longterm reduced time hemoperfusion-hemodialysis compared to standard dialysis — a preliminary crossover analysis.Trans Am Soc Artif Intern Organs1985; 31: 572.
15.
ChangT.M.S.Microcapsule artificial kidney: including update preparature and procedures and properties.Kidney Int1976; 10: S218–S224.
16.
BabbA.L., PopovichR.P., ChristopherT.G., ScribnerB.H.The genesis of the square meter-hour hypothesis.Trans Am Soc Artif Intern Organs1971; 19: 81.
