Charcoal hemoperfusion has long been used in chronic uremia as an adjunct or substitute for conventional hemodialysis.
In this study a regular combination of hemoperfusion and hemodialysis was used to cut down the weekly substitutive sessions from 3 to 2. Ten RDT patients were treated with the reduced-time schedule for 5–56 weeks. Clinical and metabolic conditions remained stable in all patients and no sign of inadequate treatment appeared. Long-term charcoal hemoperfusion was confirmed to be a safe and risk-free procedure. No change in platelets, white cells, red cells, fibrinogen and other hematochemical parameters were detected.
BonominiV., StefoniS., CascianiC.U., Taccone GallucciM., AlbertazziA., CappelliG., MioliV., BoggiR., MastrangeloF., RizzelliS.: Multicentric experience with combined hemodialysis/hemoperfusion in chronic uremia. In: Hemoperfusion, BonominiV., and ChangT.M.S. Editors, Karger, 1981 (in press).
2.
BonominiV., ZanettiM.: Cost/Benefit analysis of long-term Hemodialysis/Hemoperfusion treatment in chronic uremia (in preparation).
3.
ChangT.M.S.: Hemoperfusion alone and in series with ultrafiltration or dialysis for uremia, poisoning and liver failure.Kidney Int.10, S 305, 1976.
4.
ChangT.M.S.: Assessment of clinical trials of charcoal hemoperfusion in uremic patients.Clin. Nephrol.11, 111, 1979.
5.
ChangT.M.S.: Microencapsulation of specific sorbents for medical application. In: Sorbents and their clinical application, GiordanoC. Editor, Academic Press, 1980p. 195.
6.
ChangT.M.S.: Hemoperfusion in 1981. In: Hemoperfusion, BonominiV., and ChangT.M.S. Editors, Karger, 1981 (in press).
7.
ChangT.M.S., ChiritoE., BarreP., ColeC., HewishM.: Clinical performance characteristics of a new combined system for simultaneous hemoperfusion-hemodialysis-ultrafiltration in series.Trans. Am. Soc. Artif. Intern. Organs21, 502, 1975.
GelfandM.C., WinchesterJ.F.: Hemoperfusion results in uremia.Clin. Nephrol., 11, 107, 1979.
10.
KlinkmannH., FalkenhagenD., CourtneyJ.M.: Blood purification by hemoperfusion.Int. J. Artif. Organs, 2, 296, 1979.
11.
MartinA.M., GibbinsJ.K., KimmitJ., RennieF.: Hemodialysis and hemoperfusion in the treatment of uremic pericarditis.A study of 13 cases. Dial. Transpl., 8, 135, 1979.
12.
OdakaM., TabataY., KobayaschiH., NomuraY., SomaH., HirasawaH., SatoH.: Clinical experience of bead-shape charcoal hemoperfusion in chronic renal failure and fulminant hepatic failure. In: Chang Artificial kidney, artificial liver and artificial cells, p. 79, Plenum, New York, 1978.
13.
OtsuboO., KuzuharaK., SimadaY., YamauchiY., TakahashiI., YamadaY., OtsuboK., InouT.: Treatment of uremic peripheral neuritis by direct hemoperfusion with activated charcoal.Proc. Eur. Dial. Transpl, Assoc., 16, 731, 1979.
14.
StefoniS., ColìL., FeliciangeliG., BaldratiL., BonominiV.: Regular hemoperfusion in regular dialysis treatment.A long-term study. Int. J. Artif. Organs, 3, 348, 1980.
15.
StefoniS., FeliciangeliG., ColìL., PrandiniR., BonominiV.: The use of combined hemodialysis/hemoperfusion in chronic uremia. In: Hemoperfusion, BonominiV., and ChangT.M.S. Editors, Karger, 1981 (in press).
16.
WinchesterJ.F., GelfandM.C., KnepshieldJ.H., SchreinerG.E.: Realities in evaluating the clinical use of sorbent hemoperfusion.Int. J. Art. Organs, 2, 310, 1979.
17.
WinchesterJ.F.: Hemoperfusion in uremia. In: Sorbents and their clinical applications, GiordanoC. Editor, New York, Academic Press, 1980, p. 387.
18.
WinchesterJ.F.: Potential for hemoperfusion in uremia. In: Hemoperfusion, BonominiV., and ChangT.M.S. Editors, Karker, 1981 (in press).
19.
YatzidisD.: A convenient hemoperfusion microapparatus and charcoal for the treatment of endogenous and exogenous intoxication.Proc. Eur. Dial. Transplant. Assoc., 1, 83, 1964.
