Purpura fulminans is a rare but devastating haemorrhagic condition often associated with sepsis. Many different organisms have been implicated in the aetiology of purpura fulminans, most commonly Neisseria meningitidis and Streptococcus pneumoniae. We report a case of purpura fulminans associated with Lactobacillus paracasei liver abscess. Purpura fulminans has not previously been associated with this organism and specific bacteriological testing was used to exclude the presence of other species.
AdcockD.M., BroznaJ., MarlarR.A.Proposed classification and pathologic mechanisms of purpura fulminans and skin necrosis.Semin Thromb Hemost1990; 16: 333–340.
2.
BernardG.R., VincentJ.L., LaterreP.F., LaRosaS.P., DhainautJ.F., Lopez-RodriguezA.Efficacy and safety of recombinant human activated protein C for severe sepsis.N Engl J Med2001; 344: 699–709.
3.
ClarridgeJ.E.Impact of 16s rRNA Gene sequence analysis for identification of bacteria on clinical microbiology and infectious diseases.Clin Micro Rev2004; 17: 840–862.
4.
Saez RocaG., FernandezE., DiezJ.M., GarciaP., CastilloC., SanbonmatsuS.Splenic abscess and empyema due to Lactobacillus species in an immunocompetent host.Clin Infect Dis1998; 26: 498–499.
HusniR.N., GordonS.M., WashingtonJ.A., LongworthD.L.Lactobacillus bacteremia and endocarditis: review of 45 cases.Clin Infect Dis1997; 25: 1048–1055.
7.
BrookI., FrazierE.H.Significant recovery of nonsporulating anaerobic rods from clinical specimens.Clin Infect Dis1993; 16: 476–480.
8.
Z'GraggenW.J., FankhauserH., LammerF., BregenzerT., ConenD.Pancreatic necrosis infection due to Lactobacillus paracasei in an immunocompetent patient.Pancreatology2005; 5: 108–109.
