Pulmonary changes in field cases of bovine atypical interstitial pneumonia from Saskatchewan and Alberta were reviewed and compared with those in cattle with the same condition caused by either tryptophan or 3-methylindole. The experimentally produced changes were characterized by diffuse proliferation of alveolar pneumocytes. Similar lesions occurred in 48 field cases in animals with a history of a change in pasture or diet, whereas 107 other animals had focal exudative alveolitis, comparable to a hypersensitivity reaction. The two groups of cases are referred to as ‘dietary’ and ‘hypersensitivity atypical interstitial pneumonia', respectively. The dietary type occurred most commonly from September to November in animals 2 years and older. The hypersensitivity type occurred in younger animals throughout the year, with a peak incidence in January.
BloodD.C.:
Atypical interstitial pneumonia of cattle.Canad. vet. J.3:
40–47
(1962)
3.
CarlsonJ.R.DyerI.A.JohnsonR.J.:
Tryptophan induced interstitial pulmonary emphysema in cattle.Amer. J. vet. Res.29:
1983–1989
(1968)
4.
CarlsonJ.R.YokoyamaM.DickinsonE.O.:
Induction of pulmonary edema and emphysema in cattle and goats with 3-methylindole.Science176:
298–299
(1972)
5.
ChesneyC.F.AllenJ.R.:
Animal model of human disease: pulmonary hypertension, cor pulmonale and endocardial fibroelastosis in monocrotaline-intoxicated nonhuman primates.Amer. J. Path.70:
489–492
(1973)
6.
DickinsonE.O.:
The effects of trytophan on bovine lungs;
thesis, Pullman, Wash.
(1970)
7.
DickinsonE.O.SpencerG.R.GorhamJ.R.:
Experimental induction of an acute respiratory syndrome in cattle resembling bovine pulmonary emphysema.Vet. Rec.80:
487–489
(1967)
FaulknerC.S.EsterlyJ.R.:
Ultrastructural changes in the alveolar epithelium in response to Freund's adjuvant.Amer. J. Path.64:
559–574
(1971)
10.
FellB.F.BoyneR.KayM.WilliamsR.B.MacLeodN.A.:
Effects of feeding barley and other diets on the tissues of the calf.Vet. Rec.81:
593–598
(1967)
11.
HyslopN. S. G.:
Bovine pulmonary emphysema.Canad. vet. J.10:
251–257
(1969)
12.
JayasekaraM.U.:
Comparison of naturally occurring and tryptophan-induced bovine atypical interstitial pneumonia;
thesis, Saskatoon
(1973)
13.
LadigesW.C.DickinsonE.O.GorhamJ.R.:
Clinical and pathologic comparison of the pulmonary response during experimentally induced anaphylaxis in sheep and cattle.Amer. J. vet. Res.35:
389–392
(1974)
14.
LiebowA.A.:
New concepts and entities in pulmonary disease; in Liebow and Smith The lung.
Monogr. Internat. Acad. Path.
(Williams & Wilkins,
Baltimore1968)
15.
MakiL.:
A review of the literature of the history and occurrence of bovine pulmonary emphysema.
Symposium on acute bovine pulmonary emphysema, Laramie
1963,
pp. 1–17
16.
McCombsR.P.:
Diseases due to immunologic reactions in the lungs.New Engl. J. Med.286:
1186–1194;
1245–1252
(1972)
17.
MeisterA.:
Biochemistry of the amino acids;
2nd ed.,
vol. II,
pp. 870–874
(Academic Press,
New York1965)
18.
MerkowL.KleinermanJ.:
An electron-microscopic study of pulmonary vasculitis induced by monocrotaline.Lab. Invest.15:
547–564
(1966)
19.
MorgenrothK.:
Experimentelle Lungenfibrose als immunologische Spätreaktion. Veröffentlichungen aus der morphologischen Pathologie.
(Fischer,
Stuttgart,
1972)
20.
NicoletJ.de HallerR.HerzogJ.:
Serological investigation of a bovine respiratory disease (‘Urner Pneumonie’) resembling farmer's lung.Infect. Immunol.6:
38–42
(1972)
21.
PirieH.M.DawsonC.O.BreezeR.G.WisemanA.HamiltonJ.:
A bovine disease similar to farmer's lung: extrinsic allergic alveolitis.Vet. Rec.88:
346–351
(1971)
22.
PopovicN.A.MullaneJ.F.:
Effects of biliary obstruction on pulmonary ultrastructure in the rat.Amer. J. Path.68:
97–104
(1972)
23.
RodwellP.W.:
The occurrence and distribution of amino-acid carboxylases within the genus Lactobacillus. J. gen.Microbiol.8:
224–232
(1953)
24.
ValdiviaE.LalichJ.J.HayashiY.SonnadJ.:
Alterations in pulmonary alveoli after a single injection of monocrotaline.Arch. Path.84:
64–76
(1967)
25.
WellsP.W.EyreP.LumsdenJ.H.:
Hematological and pathological changes in acute systemic anaphylaxis in calves: effects of pharmacological agents.Canad. J. comp. Med.37:
119–129
(1973)
