Eosinophilic cytoplasmic inclusion bodies observed in the liver of a rabbit were round to oval with a clear halo and measured from 4 to 10 μm in diameter. They were nonglycogenic (PAS-positive after diastase treatment) and stained with burnt Sudan black, indicating bound lipid. The inclusion bodies, when examined by electron microscopy, were composed of a uniform amorphous material. They varied in size and density. It is suggested that the bodies were enlarged lysosomes and were nonviral.
FindlayG. M.:
Cytological changes in the liver in Rift Valley fever, with special reference to the nuclear inclusions.
Brit. J. exp. Path.14:
207–219
(1933).
3.
HolmesD. DSmithP. D.:
Inclusion bodies in hepatic cytoplasm of dogs and rats after administering endotoxin.
Amer. J. vet. Res.30:
811–815
(1969).
4.
LaddsP.W.StrafussA.C.:
Eosinophilic cytoplasmic bodies in a bovine liver.
Cornell Vet.61:
486–489
(1971).
5.
MurtiG.S.BorgmannR.:
Intracytoplasmic periodic acid-Schiff-positive nonglycogenic globules in canine liver. Their histochemical characterization.
Amer. J. vet. Res.26:
63–67
(1965).
6.
PopperH.ParonettoF.BarkaT.:
PAS-positive structures of nonglycogenic character in normal and abnormal liver.
Arch. Path.70:
300–313
(1960).
