A total of four children with osteogenesis imperfecta, three with type I and one with type III forms of the disease, were treated with synthetic salmon calcitonin for 18 – 24 months. The annual fracture rate was decreased during calcitonin therapy compared with the period preceding it. No patient presented a marked inflexion in linear growth and a transient improvement was even noticed in two cases.
CastellsSColbertCChakrabartiC: Therapy of osteogenesis imperfecta with synthetic salmon calcitonin. J Pediatr1979; 95: 807–811.
2.
ShaiFBakerRKWallachS: The clinical and metabolic effects of porcine calcitonin on Paget's disease of bone. J Clin Invest1971; 50: 1927–1940.
3.
NishiYHyodoSIshidaM: Effect of porcine calcitonin therapy on vitamin D metabolism and clinical response in a patient with osteogenesis imperfecta. Acta Paediatr Scand1983; 72: 149–152.
4.
CantalamessaLCataniaARaschiniE: Inhibitory effect of calcitonin in man. Metabolism1978; 27: 987–992.
5.
MinamitaniNChiharaKKajiH: Inhibitory effect of [Asn1,7)-eel calcitonin on growth hormone secretion in conscious, freely moving, male rats. Endocrinology1985; 117: 347–353.
6.
SillenceDOSennADanksDM: Genetic heterogenicity in osteogenesis imperfecta. J Med Genet1979; 16: 101–116.
7.
TannerJM: Physical growth and development. In: Textbook of Paediatrics (ForfarJOArneilGC, eds). London: Churchill Livingstone, 1984; pp 278–330.
8.
TannerJMWhitehouseRH: Clinical longitudinal standards for height, weight, height velocity, weight velocity, and stages of puberty. Arch Dis Child1976; 51: 170–179.
9.
GreulichWWPyleSI: Radiographic Atlas of Skeletal Development of Hand and Wrist, 2nd edn. New York: Stanford University Press, 1959.
10.
AlbrightJA: Systemic treatment of osteogenesis imperfecta. Clin Orthop1981; 159: 88–96.
11.
LanesRToledoTObregonO: Calcitonin and calcium therapy in an infant with osteogenesis imperfecta congimte. J Am Coll Nutr1983; 2: 101–106.
12.
BaronRSaffarGL: A quantitative study of effects of prolonged calcitonin treatment on alveolar bone remodeling in the golden hamster. Calcif Tiss Res1977; 22: 265–274.
