Rubella Vaccine – How ‘Reactogenic’ is it?

Abstract

Girls (231) aged 11—13 years were allocated at random to receive one of two RA27/3 rubella vaccines. A high incidence of minor and self-limiting side-effects were found by intensive follow-up. No difference in reactogenicity could be found between vaccines from the Institut Merieux and Wellcome. This study confirms the highly acceptable risk/benefit ratio of vaccination against rubella in the U.K.