Twenty-one patients between the ages of 68 and 89 years with osteoarthrosis of hips and/or knee joints were studied. One group was treated with fenoprofen 300 mg t.d.s. for 5 days, and the other group with 600 mg t.d.s. for 5 days. No therapeutic advantage was found with the higher dose, and the side-effects were minimal on either dosage. Treatment of elderly patients with the smaller dose is recommended.
Get full access to this article
View all access options for this article.
References
1.
Data Sheet Compendium (1979–1980).
2.
GoldingJ RDayA T (1978) A comparison of fenoprofen with indomethacin and placebo in osteoarthrosis of large joints. Pharmatherapeutica2, 2, 103.
3.
Martlndale's Pharmacopoeia (1979) 27th edition, p 191.
4.
ParkeD V (1978) Metabolism of drugs in the elderly. British Journal of Clinical Practice32, (Suppl. 2), 22.
5.
WilsonL ABrassW (1973) Brief assessment of the mental state in geriatric domiciliary practice: The usefulness of the mental status questionnaire. Age and Ageing2, 92.
6.
WojtuleskiJ AHartF DudleyHuskissonE C (1974) Fenoprofen in treatment of osteoarthrosis of hip and knee. British Mediccd Journal2, 475.