The Effect of Bumetanide and Frusemide on Frequency of Micturition

Abstract

General practice patients with mild to moderate congestive cardiac failure recorded their frequency of micturition after taking frusemide 40 mg or bumetanide 1 mg at 8 a.m. or bumetanide 1 mg at 6 p.m. Morning doses of bumetanide or frusemide caused a similar pattern of urinary frequency, although the period of increased frequency appeared to be shorter with bumetanide.

If an evening diuresis is required, bumetanide should be given between 4 and 6 p.m. The use of potent and short acting diuretics such as bumetanide allow the physician and patient scope to decide upon the most appropriate time for administration and so reduce major disruptions in the patient's daily routine.