Opipramol (Insidon, Geigy) is an iminostilbene derivative belonging to the dibenzazepine group with a nucleus similar to that of imipramine and has been regarded principally as anti-depressant in its action, but its perphenazine like side chain suggests that it might have additional anxiolytic properties.
In a double-blind comparison of opipramol and trifluoperazine the symptom ‘anxiety’ was found to be statistically more improved in the opipramol group of patients.
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