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Abstract

Individuals with ocular and oculocutaneous albinism (OCA) have significantly reduced visual acuity (VA) resulting in visual impairment (VI). The aim is to report on the visual function of adolescents with OCA and their quality of life (QoL) in terms of their visual ability. A total of 28 adolescents with OCA participated in this study. Tests of visual function included distance VA, refractive error, contrast sensitivity (CS), and colour vision. The Cardiff Visual Ability Questionnaire for Children (CVAQC) was used to assess visual ability. All participants presented with cutaneous hypopigmentation and nystagmus, while only two had strabismus. A mean myopic refractive error was found, and with-the-rule (WTR) astigmatism was most common. The mean best-corrected VA was 0.81 ± 0.17 logMAR and 0.81 ± 0.18 logMAR in the right and left eyes, respectively. The mean CS with the best refractive correction was 1.23 ± 0.33 log CS in the right eye and 1.29 ± 0.33 log CS in the left eye. The mean Cardiff visual ability score was −0.37 ± 0.79 log units. The variation of refractive errors and the magnitude thereof underscores the need for regular eye examinations in individuals with OCA. The majority of participants had moderate VI, and these participants had a better mean Cardiff visual ability score than those with severe VI. Similarly, participants with normal binocular CS had a better Cardiff visual ability score than those with a loss of CS.

Keywords

Cardiff Visual Ability Questionnaire for children Cardiff visual ability score contrast sensitivity oculocutaneous albinism quality of life visual ability visual impairment

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References

Abdullah

M. S.

Jani

Abdullah

(2012). A preliminary study to compare motor skills ability among people with albinism in Malaysia and Australia. Jurnal Pendidikan Bitara, 5(1), 1–12.

Atchison

D. A.

Bowman

K. J.

Vingrys

A. J.

(1991). Quantitative scoring methods for D15 panel tests in the diagnosis of congenital color vision deficiencies. Optometry and Vision Science, 68(1), 41–48. https://doi.org/10.1097/00006324-199101000-00007

Bailey

I. L.

Hall

(1989). Introduction. In Bailey

I. L.

Hall

(Eds.), Visual impairment: An overview (1st ed., pp. 1–2). American Foundation for the Blind.

Borish

I. M.

Benjamin

W. J.

(2006). Monocular and binocular subjective refraction. In Benjamin

W. J.

(Ed.), Borish’s clinical refraction (2nd ed., pp. 790–898). Elsevier. https://doi.org/10.1016/B978-0-7506-7524-6.50025-9

Cole

B. L.

(2007). Assessment of inherited colour vision defects in clinical practice. Clinical and Experimental Optometry, 90(3), 157–175. https://doi.org/10.1111/j.1444-0938.2007.00135.x

DeCarlo

D. K.

Woo

G. C.

(2006). Patients with low vision. In Benjamin

W. J.

(Ed.), Borish’s clinical refraction (2nd ed., pp. 1591–1618). Elsevier. https://doi.org/10.1016/B978-0-7506-7524-6.50041-7

Elliott

D. B.

(2006). Contrast sensitivity and glare testing. In Benjamin

W. J.

(Ed.), Borish’s clinical refraction (2nd ed., pp. 247–288). Elsevier. https://doi.org/10.1016/B978-0-7506-7524-6.50013-2

Ganesh

Sethi

Srivastav

Chaudhary

Arora

(2013). Impact of low vision rehabilitation on functional vision performance of children with visual impairment. Oman Journal of Ophthalmology, 6(3), 170–174. https://doi.org/10.4103/0974-620X.122271

Healey

Jackson

A. J.

Willoughby

C. E.

McClelland

J. F.

(2010). Albinism: What the GOS optometrist needs to know. Optometry in Practice, 11(2), 57–76.

10.

Jhetam

Mashige

K. P.

(2019). Ocular findings and vision status of learners with oculocutaneous albinism. African Vision and Eye Health, 78(1), Article a466. https://doi.org/10.4102/aveh.v78i1.466

11.

Kanski

J. J.

Bowling

(2016). Hereditary fundus dystrophies. In: Salmon

(ed.) Kanski’s Clinical Ophthalmology: A Systematic Approach (pp. 641–680). Elsevier.

12.

Khadka

McAlinden

Pesudovs

(2013). Quality Assessment of Ophthalmic Questionnaires. Optometry and Vision Science, 90(8), 720–744. https://doi.org/10.1097/OPX.0000000000000001

13.

Khadka

Ryan

Margrain

T. H.

Woodhouse

J. M.

Davies

(2012). Listening to voices of children with a visual impairment: A focus group study. British Journal of Visual Impairment, 30(3), 182–196. https://doi.org/10.1177/0264619612453105

14.

Khanal

Pokharel

Kandel

(2016). Visual deficits in Nepalese patients with oculocutaneous albinism. Journal of Optometry, 9(2), 102–109. https://doi.org/10.1016/j.optom.2015.01.002

15.

Loshin

D. S.

Browning

R. A.

(1983). Contrast sensitivity in albinotic patients. Optometry and Vision Science, 60(3), 158–166. https://doi.org/10.1097/00006324-198303000-00003

16.

Maia

Volpini

B. M. F.

Santos

G. A.

dos Rujula

M. J. P.

(2015). Quality of life in patients with oculocutaneous albinism. Anais Brasileiros de Dermatologia, 90(4), 513–517. https://doi.org/10.1590/abd1806-4841.20153498

17.

Milling

A. F.

O’Connor

A. R.

Newsham

(2014). The importance of contrast sensitivity testing in children. British and Irish Orthoptic Journal, 11(1), 9–14. http://livrepository.liverpool.ac.uk/id/eprint/2032880

18.

Obstfeld

(1982). Emmetropia and ametropia. In Obstfeld

(Ed.), Optics in vision (2nd ed., pp. 43–49). Butterworth.

19.

Owsley

Sloane

M. E.

(1987). Contrast sensitivity, acuity, and the perception of real-world targets. British Journal of Ophthalmology, 71(10), 791–796. https://doi.org/10.1136/bjo.71.10.791

20.

Rainey

Elsman

E. B. M.

van Nispen

R. M. A.

van Leeuwen

L. M.

van Rens

G. H. M. B.

(2016). Comprehending the impact of low vision on the lives of children and adolescents: A qualitative approach. Quality of Life Research, 25(10), 2633–2643. https://doi.org/10.1007/s11136-016-1292-8

21.

Raj

L. J.

(2007). How to assess and plan for the management of visually challenged children in the context of multiple ‘different-abilities’. Community Eye Health Journal, 20(62), 91–92.

22.

Read

S. A.

Collins

M. J.

Carney

L. G.

(2007). A review of astigmatism and its possible genesis. Clinical and Experimental Optometry, 90(1), 5–19. https://doi.org/10.1111/j.1444-0938.2007.00112.x

23.

Sampath

Bedell

H. E.

(2002). Distribution of refractive errors in albinos and persons with idiopathic congenital nystagmus. Optometry and Vision Science, 79(5), 292–299.

24.

Schwering

S. M.

Kumar

Bohrmann

Msukwa

Kalua

Kayange

Spitzer

M. S.

(2015). Refractive errors, visual impairment, and the use of low-vision devices in albinism in Malawi. Graefe’s Archive for Clinical and Experimental Ophthalmology, 253(4), 655–661. https://doi.org/10.1007/s00417-015-2943-0

25.

Udeh

N. N.

Eze

B. I.

Onwubiko

S. N.

Arinze

O. C.

Onwasigwe

E. N.

Umeh

R. E.

(2014). Oculocutaneous albinism: Identifying and overcoming barriers to vision care in a Nigerian population. Journal of Community Health, 39(3), 508–513. https://doi.org/10.1007/s10900-013-9787-5

26.

West

S. K.

(2002). How does visual impairment affect performance on tasks of everyday life? Archives of Ophthalmology, 120(6), 774–780. https://doi.org/10.1001/archopht.120.6.774

27.

Wildsoet

C. F.

Oswald

P. J.

Clark

(2000). Albinism: Its implications for refractive development. Investigative Ophthalmology and Visual Science, 41(1), 1–7.

28.

Woods

R. L.

Wood

J. M.

(1995). The role of contrast sensitivity charts and contrast letter charts in clinical practice. Clinical and Experimental Optometry, 78(2), 43–57. https://doi.org/10.1111/j.1444-0938.1995.tb00787.x

Visual function and visual ability in adolescents with oculocutaneous albinism

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