The purpose of this integrative review of the literature is to synthesize the current evidence and identify gaps in knowledge regarding the effectiveness of acupuncture to treat chemotherapy-induced peripheral neuropathy (CIPN). PubMed, CINAHL, Web of Science, and Cochrane Review databases were searched using inclusion criteria: keywords acupuncture, cancer, and peripheral neuropathy, published in English, between 2009 and 2019. Sixteen articles met the inclusion criteria. The literature indicates that acupuncture is generally well tolerated by patients with cancer, and a majority of patients with CIPN reported decreased pain and increased quality of life after receiving acupuncture treatment. A comprehensive understanding of the ability of acupuncture to treat CIPN is limited by variability of acupuncture techniques and inconsistency in measures of evaluation.
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2.
BaoT.BasalC.SeluzickiC.LiS. Q.SeidmanA. D.MaoJ. J. (2016). Long-term chemotherapy-induced peripheral neuropathy among breast cancer survivors: Prevalence, risk factors, and fall risk. Breast Cancer Research and Treatment, 159(2), 327–333. https://doi.org/10.1007/s10549-016-3939-0
3.
BaoT.GoloubevaO.PelserC.PorterN.PrimroseJ.HesterL.SadowskaM.LapidusR.MedeirosM.LaoL.DorseyS. G.BadrosA. Z. (2014). A pilot study of acupuncture in treating bortezomib-induced peripheral neuropathy in patients with multiple myeloma. Integrative Cancer Therapies, 13(5), 396–404. https://doi.org/10.1177/1534735414534729
4.
BaoT.SeidmanA. D.PiulsonL.VertosickE.ChenX.VickersA. J.BlinderV. S.ZhiW. I.LiQ.VahdatL. T.DicklerM. N.RobsonM. E.MaoJ. J. (2018). A phase iia trial of acupuncture to reduce chemotherapy-induced peripheral neuropathy severity during neoadjuvant or adjuvant weekly paclitaxel chemotherapy in breast cancer patients. European Journal of Cancer, 101, 12–19. https://doi.org/10.1016/j.ejca.2018.06.008
5.
BavieraA. F.OlsonK.de PaulaJ. M.TonetiB. F.SawadaN. O. (2019). Acupuncture in adults with chemotherapy-induced peripheral neuropathy: A systematic review. Revista Latino-Americana De Enfermagem, 27, e3126. https://doi.org/10.1590/1518-8345.2959.3126
6.
Ben-AryeE.RiverY.KeshetY.LavieO.IsraeliP.SamuelsN. (2018). Effect of a complementary/integrative medicine treatment program on taxane-induced peripheral neuropathy: A brief report. International Journal of Gynecological Cancer, 28(5), 1045–1049. https://doi.org/10.1097/IGC.0000000000001246
7.
ChienT. J.LiuC. Y.FangC. J.KuoC. Y. (2019). The efficacy of acupuncture in chemotherapy-induced peripheral neuropathy: Systematic review and meta-analysis. Integrative Cancer Therapies, 18, 1–10. https://doi.org/10.1177/1534735419886662
8.
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9.
FranconiG.ManniL.SchroederS.MarchettiP.RobinsonN. (2013). A systematic review of experimental and clinical acupuncture in chemotherapy-induced peripheral neuropathy. Evidence-Based Complementary and Alternative Medicine, 2013, 1–7. https://doi.org/10.1155/2013/516916
10.
GarciaM. K.CohenL.GuoY.ZhouY.YouB.ChiangJ.OrlowskiR. Z.WeberD.ShahJ.AlexanianR.ThomasS.RomagueraJ.ZhangL.BadilloM.ChenY.WeiQ.LeeR.DelasalleK.GreenV.WangM. (2014). Electroacupuncture for thalidomide/bortezomib-induced peripheral neuropathy in multiple myeloma: A feasibility study. Journal of Hematology & Oncology, 7, 41. https://doi.org/10.1186/1756-8722-7-41
11.
GreenleeH.CrewK.CapodiceJ.AwadD.BuonoD.ShiZ.JeffresA.WyseS.WhitmanW.TrivediM. S.KalinskyK.HershmanD. L. (2016). Randomized sham- controlled pilot trial of weekly electro-acupuncture for the prevention of taxane-induced peripheral neuropathy in women with early stage breast cancer. Breast Cancer Research and Treatment, 156(3), 453–464. https://doi.org/10.1007/s10549-016-3759-2
12.
HammondE.PitzM.ShayB. (2019). Neuropathic pain in taxane-induced peripheral neuropathy: Evidence for exercise in treatment. Neurorehabilitation and Neural Repair, 33(10), 792–799. https://doi.org/10.1177/1545968319860486
13.
HanX.WangL.ShiH.ZhengG.HeJ.WuW.ShiJ.WeiG.ZhengW.SunJ.HuangH.CaiZ. (2017). Acupuncture combined with methylcobalamin for the treatment of chemotherapy-induced peripheral neuropathy in patients with multiple myeloma. BMC Cancer, 17(1), 1–7. https://doi.org/10.1186/s12885-016-3037-z
14.
HershmanD. L.LacchettiC.DworkinR. H.Lavoie SmithE. M.BleekerJ.CavalettiG.ChauhanC.GavinP.LavinoA.LustbergM. B.PaiceJ.SchneiderB.SmithM. L.SmithT.TerstriepS.Wagner-JohnstonN.BakK.LoprinziC. L. (2014). Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers: American Society of Clinical Oncology clinical practice guideline. Journal of Clinical Oncology, 32(18), 1941–1967. https://doi.org/10.1200/JCO.2013.54.0914
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LiK.GiustiniD.SeelyD. (2019). A systematic review of acupuncture for chemotherapy- induced peripheral neuropathy. Current Oncology, 26(2), E147–E154. https://doi.org/10.3747/co.26.4261
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22.
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24.
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26.
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