This article represents the first description of a complete pharmacokinetic data management system. This system uses an HP-3357 computer for data acquisition and an IBM mainframe for sample processing. This system is unique in that it provides sample management capabilities, automatic data collection, GLP documentation, and estimates of pharmacokinetic parameters. This computer system has greatly reduced the time necessary to analyze the data from a pharmacokinetic study. Furthermore, the reliability of the data is increased by eliminating data transposition errors and by forcing uniformity in sample processing.
