Acute fatty liver of pregnancy (AFLP) and acute pancreatitis are peculiar complications of pregnancy. When acute pancreatitis occurs co-incidentally with acute fatty liver of pregnancy, mortality is high. Here, we report a case of a 22-year-old lady in her 36th week of gestation, who presented with pre-eclampsia, acute fatty liver of pregnancy and acute pancreatitis. She fulfilled six Swansea criteria for diagnosis of AFLP, and the diagnosis of acute pancreatitis was based on clinical suspicion, elevated pancreatic enzymes and the sonographic appearance of a swollen pancreatic head.
RajasriQSresthaRMitchellJ. Acute fatty liver of pregnancy (AFLP) an overview. J Obstet Gynaecol2007; 27: 237–240.
2.
BelligLL. Maternal acute fatty liver of pregnancy and the associated risk for long-chain 3-hydroxyacyl-coenzyme a dehydrogenase (LCHAD) deficiency in infants. Adv Neonatal Care2004; 4: 26–32.
3.
Bacq Y. The liver diseases in pregnancy. In: Schiff ER, Sorrell MF, Schiff L, et al. (eds) Schiff's diseases of the liver. 10th ed. Philadelphia: Lippincott: Williams and Wilkins, 2006, pp.1281–1304.
4.
SunYFanCWangS. Clinical analysis of 16 patients with acute pancreatitis in the third trimester of pregnancy. Int J Clin Exp Pathol2013; 6: 1696–1701.
5.
ToskesPP. Hyperlipidemic pancreatitis. Gastroenterol Clin North Am1990; 19: 783–791.
AbdullahBPillaiTKCheenLH, et al.Severe acute pancreatitis in pregnancy. Case Rep Obstet Gynecol2015; 2015: 239068–239068.
8.
LoweSABrownMADekkerGA, et al.Guidelines for the management of hypertensive disorders of pregnancy 2008. ANZJOG2009; 49: 242–246.
9.
LiuGShangXYuanB, et al.Acute fatty liver of pregnancy: analysis on the diagnosis and treatment of 15 cases. J Reprod Med2016; 61: 282–286.
10.
SibaiBM. Imitators of severe pre-eclampsia. Semin Pernatol2009; 33: 196–205.
11.
LimWHDhanarajB. Diagnostic dilemma: is it severe pre-eclampsia or acute fatty liver of pregnancy. Woman Health2014; 16: 60–62.
12.
LauHChenYHuangJ, et al.Acute fatty liver of pregnancy in a Taiwanese tertiary care center: a retrospective review. Taiwan J Obstet Gynecol2010; 49: 156–159.
13.
XiongHFLiuJYGuoLM, et al.Acute fatty liver of pregnancy: over six months follow-up study of twenty-five patients. World J Gastroenterol2015; 21: 1927–1931.ts.
14.
Rodrigo N and Hocking S. Transient diabetes insipidus in a post-partum woman with pre-eclampsia associated with residual placental vasopressinase activity. Endocrinol Diabetes Metab Case Rep 2018; 20.
15.
HerreraEDesoyeG. Maternal and fetal lipid metabolism under normal and gestational diabetic conditions. Hormone Mol Biol Clin Investig2016; 26: 109–127.
16.
PrakashJGanigerVC. Acute kidney injury in pregnancy-specific disorders. Indian J Nephrol2017; 27: 258–270.
17.
MoldenhauerJO'BrienJBartonJ, et al.Acute fatty liver of pregnancy associated with pancreatitis: a life-threatening complication. Am J Obstet Gynecol2004; 190: 502–505.
18.
HernandezAPetrovMSBrooksDC, et al.Acute pancreatitis and pregnancy: a 10-year single center experience. J Gastrointest Surg2007; 11: 1623–1627.
19.
KnightMNelson-PiercyCKurinczukJJ, et al.A prospective national study of acute fatty liver of pregnancy in the UK. Gut2008; 57: 951–956.