Cryptosporidiosis presenting as reversible acute allograft dysfunction mimicking rejection in a renal transplant recipient

Abstract

Diarrhoeal illnesses in renal transplant recipients are common in tropical regions but may have significant implications beyond gastro-intestinal morbidity. Cryptosporidiosis, although common in tropical settings, may present as acute allograft dysfunction through a haemodynamic mechanism, closely mimicking rejection. Recognition of this reversible cause is essential to avoid unnecessary escalation of immuno-suppression and to ensure timely management. Gastro-intestinal infections are often considered benign and self-limiting, but their systemic consequences in immunosuppressed hosts are frequently under-recognised.