Dementia in general and Alzheimer's disease in particular represent conditions where new findings are being made rapidly. Some of these developments will lead to progress of increasing clinical value to patients and their carers. This review will begin with some general points about dementia before considering current developments in Alzheimer's disease and other specific dementias in more detail.
The Quality Standards Subcommittee ofthe American Academy of Neurology. Practice parameters for diagnosis and evaluation of dementia (summary statement). Neurology1994; 44, 2203–06.
2.
HofmanARoccaWABrayneC. The prevalence of dementia in Europe: A collaborative study of 1980–1990 findings. Int J Epidemiol, 1991; 20, 736–48.
3.
FolsteinMFFolsteinSEMcHughPR. “Mini-mental state”: A practical method for grading the cognitive state of patients for the clinician. J PsychiatrRes, 1975; 12, 189–98.
4.
LendonCLAshallFGoateAM. Exploring the etiology of Alzheimer disease using molecular genetics. J Amer Med Ass, 1997; 277: 825–31.
5.
OrrellMWoodsB. Tacrine and psychological therapies in dementia — No contest?Int J Ger Psychiatry1996; 11: 189–92.
6.
CummingsJLKauferD. Neuropsychiatry aspects of Alzheimer's disease: The cholinergic hypothesis revisited. Neurology, 1996; 47, 876–83.
7.
SanoMErnestoMSThomasRG. A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The New Engl J Med, 1997; 17, 1216–17.
8.
American Psychiatric Association. Practice guideline for the treatment of patients with Alzheimer's disease and other dementias of late life. Am J Psychiatry1997: 154 (5 suppl).
9.
SnowdonDAGreinerLHMortimerJA. Brain infarction and the clinical expression of Alzheimer disease. J Amer Med Ass, 1997; 277, 813–17.
10.
McKeithIGGalaskoDKosakaK. Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): Report of the consortium on DLB international workshop. Neurology, 1996; 47: 1113–24.
11.
BrunAEnglundEGustafsonL. Clinical and neuropathological criteria for fronto-temporal dementia. J Neurol Neurosurg Psychl, 1994; 57, 416–18.
