Abstract
This research is part of a study on scaling-up middle school science curriculum units in a large, diverse public school system. Chemistry That Applies (CTA), a guided inquiry unit based on conceptual change theory and highly rated according to the Project 2061 Curriculum Analysis, was implemented in five middle schools matched demographically with five comparison schools (N = 2,282 students). Eighth grade CTA students outscored their peers overall and when data were disaggregated, with small to medium effect sizes. Of particular interest are students with disabilities in general education science classrooms (n = 202 students with complete assessment records). Those who used CTA significantly outscored their comparison peers on the posttest, with a small to medium effect size.
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