High-Dose Hook Effect in a Two-Site IRMA for Measuring Thyrotropin

Rodbard D Feldman Y Jaffe ML Miles LEM . Kinetics of two-site immunoradiometric (‘sandwich’) assays—II. Studies on the nature of the ‘high-dose hook effect.’ Immunochemistry 1978; 15: 77–82.

Garrett PE . The hook: Who's got it? when does it matter? what can you do about it? J Clin Immunoassay 1986; 9: 170–1.

Schwartz JG Brown RW Gage CL . How accurate are your IgE determinations? Clin Chem 1988; 34: 1925.

Wolf BA Garrett NC Nahm MH . The ‘hook effect’: High concentration of prostate-specific antigen giving artifactually low values on one-step immunoassay. N Engl J Med 1989; 320: 1755–6.

Garrett PE . Double feature: Case of the phantom cobalt and the hook revisited. J Clin Immunoassay 1989; 12: 135–6.