Wegener's granulomatosis is an uncommon autoimmune disease. It has a peak incidence in the fifth decade of life, with a slight male predominance. Nasal problems are the predominant presentation, with rare otological manifestations. We report 2 cases of Wegener's granulomatosis presenting as mastoiditis in 2 young female patients. We conclude that young patients presenting with mastoiditis unresponsive to conventional medical and surgical therapy should be investigated for Wegener's granulomatosis.
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McDonaldTJDeRemeeRA. Head and neck involvement in Wegener's granulomatosis. In: GrossWL ed. ANCA-associated vasculitides: immunological and clinical aspects.New York, NY: Plenum Press, 1993: 309–13.
McDonaldTJDeRemeeRAWeilandLH. Wegener's granulomatosis and polymorphic reticulosis — Two diseases or one? Experience with 90 patients. Arch Otolaryngol1981; 107: 141–4.
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FauciASHaynesBFKatzPWolffSM. Wegener's granulomatosis: Prospective clinical and therapeutic experience with 85 patients for over 21 years. Ann Intern Med1983; 98: 76–85.
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ItoYShinogoJYutaAOkadaETakiMMatsukageH. A case report of Wegener's granulomatosis limited to the ear. Auris Nasus Larynx1991; 18: 281–9.
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WegenerF.Sog Wegenersche Granulomatose. In: StaemmlerMM ed. Lehrbuch der speziellen pathologischen anatomie.Vol 1.Berlin, Germany: De Gruyter, 1966: 226.
20.
IllumPThorlingK. Wegener's granulomatosis. Long-term results of treatment. Ann Otol Rhinol Laryngol1981; 90: 231–5.
