Abstract
Aims:
The aim of this study was to report the short-term clinical and angiographic outcomes after an intravitreal injection of bevacizumab in eyes with refractory diabetic macular edema.
Methods:
Patients who had been treated with both grid-laser photocoagulation and intravitreal trimacinolone acetonide injections for diabetic macular edema received intravitreal bevacizumab (0.125 mg/0.05 mL). Snellen visual acuity testing and fluorescien angiography were performed before and 1 month after the injection for each patient.
Results:
Seventeen (17) eyes of 16 patients were included in the study. All patients completed 6 weeks of follow-up. Visual acuity improved in 12 eyes (70%) and remained the same in 5 eyes (30%). Eight (8) eyes (47%) revealed a marked improvement of macular edema, 6 eyes (35%) revealed mild improvement, and 3 eyes (18%) had no change. None of the patients developed local or systemic adverse events.
Conclusions:
Intravitreal injection of bevacizumab may be effective in the treatment of refractory diabetic edema unresponsive to laser photocoagulation and an intravitreal triamcinolone injection.
Get full access to this article
View all access options for this article.