Abstract
ABSTRACT
Arachidonic acid (AA) metabolism in the human and bovine retina was assessed. This study demonstrates that the human and bovine retina can synthesize prostaglan-din (PG) E2, F2α, I2, D2 and thromboxane A2 from 14C-AA. This tissue also synthesized leukotriene (LT) B4, and 12-hydroxyeicosatetraenoic acid (12-HETE). Although human and bovine retina metabolized AA into PGs and LTs, the ability to synthesize these products was considerably less than some other ocular tissues of various species.
Get full access to this article
View all access options for this article.