Committee on Carcinogenicity of Chemicals in Food,Consumer Products and the Environment Statement on ILSI/HESI Research Programme on Alternative Cancer Models
ICH (2000). International Conference on Harmonisation of Technical Requirements for the Registration of Pharmaceuticals for human use (ICH). Harmonised Tripartite guideline, Testing for carcinogenicity of pharmaceuticals, 1997. Geneva, Switzerland.
2.
Blain PG, Battershill JM, Venitt S., Cooper CC, Fielder RJ (1998). Consideration of short-term carcinogenicity tests using transgenic mouse models. In: Current Issues in Mutagenesis and Carcinogenesis, No. 87, Mutation Research, 403: 259—263.
3.
Robinson DE, MacDonald J. (2001). Background and Framework for ILSI's collaborative evaluation program on alternative models for carcinogenicity assessment. Toxicol Pathol29(Suppl): 13—19.
4.
Popp JA (2001). Criteria for the evaluation of studies in transgenic models. Toxicol Pathol29(Suppl): 20—23.
5.
French JE, Stoner R., Donehower LA (2001). The Nature of the heterzygous Trp53 Knockoutmodelforthe identificationmutagenic carcinogens. Toxicol Pathol29(Suppl): 24—29.
6.
Storer RD, et al (2001). p53+/− Hemizygous knockout mouse: Overview of available data. Toxicol Pathol29(Suppl): 30—50.
7.
Tennant RW, Stasiewicz S., Easton WC, Mennear JH, Spalding JW (2001). The Tg.AC (v-Ha-ras) transgenic mouse: Nature of the model. Toxicol Pathol29(Suppl): 51—59.
8.
Eastin WC, et al (2001). Tg.AC genetically altered mouse: Assay working group overview of available data. Toxicol Pathol29(Suppl): 60— 80.
9.
Van Steeg H. , de Vries A., van Oostron CThM , Van Benthem, Beems RB, van Kreijl CF (2001). DNA Repair Deficient Xpa and Xpa/p53+/− Knockout Mice: Nature of the models. Toxicol Pathol29(Suppl): 109— 117.
10.
Coen F., et al (2001). Xpa and Xpa/p53+/− Knockout Mice: Overview of Available Data. Toxicol Pathol29(Suppl): 117—127.
11.
Tamaoki N. (2001). The rasH2 Transgenic mouse. Nature of model and mechanistic study of tumourigenesis. Toxicol Pathol29(Suppl): 81—89.
12.
Usui T., et al (2001). CB6F1-rasH2 mouse: Overview of available data. Toxicol Pathol29(Suppl): 90—108.
13.
Department of Health (1998 ). 1998 Annual Report of the Committees on Toxicity,MutagenicityandCarcinogenicityofChemicalsinFood, Consumer Products and the Environment. Published Department of Health, London, England, 21145 1P 1-5K Mar 00 (OAK).
14.
Van Tungeln LS, Beland FA, Casciano DA, Kadlubar FK, Fu PP (2001). Neonatal mouse model for short term carcinogenesis testing. Toxicol Pathol29(Suppl): 198—199.
15.
McClain R., et al (2001). Neonatal mouse model: Review of methods and results. Toxicol Pathol29(Suppl): 128—137.
16.
Maulth RJ, Gibson DP, Bunch RJ, Caster L. (2001). The Syrian hamster embryo (SHE) cell transformation assay. Review of the methods and results from ILSI/HESI program on Alternative Cancer Testing. Toxicol Pathol29(Suppl): 138—146.