Discontinuation of indomethacin in chronic paroxysmal hemicrania (CPH) usually causes relapse of symptoms within a few days. A patient with characteristic symptoms of CPH is reported. The patient had daily attacks of unilateral headache accompanied by ipsilateral lacrimation and conjunctival injection, a frequency of attacks between four and fourteen per day, and never a headache-free day. He was treated with indomethacin, and all symptoms disappeared within 24 h. After three months indomethacin was discontinued. Six months after that the patient was still symptom-free.
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