Abstract
Clinical findings of four female members from one family with familial hemiplegic migraine are briefly summarized. Cerebral blood flow (CBF) studies using the xenon 133 inhalation method were carried out during and between hemiplegic attacks in two of the family members. CBF was significantly lower over the affected hemisphere during attacks, while equal flow on both sides was seen in headache free periods. The findings indicate that cerebral perfusion is altered, but not necessarily decreased during attacks of familial hemiplegic migraine.
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