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Research article

First published 2007

FTY720 Story. Its Discovery and the following Accelerated Development of Sphingosine 1-Phosphate Receptor Agonists as Immunomodulators Based on Reverse Pharmacology

Kunitomo Adachi, Kenji Chiba

Perspectives in Medicinal Chemistry

Free access

Research article

First published 2008-12

β-Arrestin Recruitment Assay for the Identification of Agonists of the Sphingosine 1-Phosphate Receptor EDG1

Miranda M.C. van Der Lee, Maaike Bras, Chris J. van Koppen [...]

Journal of Biomolecular Screening

Free access

Other

First published 2003-10

Comparative Analysis of Functional Assays for Characterization of Agonist Ligands at G Protein-Coupled Receptors

Anke Niedernberg, Sorin Tunaru, Andree Blaukat [...]

Journal of Biomolecular Screening

Retricted access

Research article

First published 2011-2

Fingolimod

Dennis J. Cada, Terri L. Levien, Danial E. Baker

Hospital Pharmacy

Retricted access

Research article

First published 2018-10

The Xenopus tadpole: An in vivo model to screen drugs favoring remyelination

Abdelkrim Mannioui, Quentin Vauzanges, Jean Baptiste Fini [...]

Multiple Sclerosis Journal

Free access

Research article

First published 2011-7

S1P 4 Receptor Mediates S1P-Induced Vasoconstriction in Normotensive and Hypertensive Rat Lungs

Hiroki Ota, Michelle A. Beutz, Masako Ito [...]

Pulmonary Circulation

Free access

Research article

First published 2014-3

No Differences Observed among Multiple Clinical S1P 1 Receptor Agonists (Functional Antagonists) in S1P 1 Receptor Down-regulation and Degradation

Susan Lukas, Lori Patnaude, Sokol Haxhinasto [...]

Journal of Biomolecular Screening

Free access

Research article

First published 2013-10

Predictability of Peripheral Lymphocyte Reduction of Novel S1P 1 Agonists by In Vitro GPCR Signaling Profile

Han Xu, Michele McElvain, Mike Fiorino [...]

Journal of Biomolecular Screening

Retricted access

Research article

First published 2010-06

FTY720 Promotes Local Microvascular Network Formation and Regeneration of Cranial Bone Defects

Caren E. Petrie Aronin, Lauren S. Sefcik, Sunil S. Tholpady [...]

Tissue Engineering Part A: Research Advances

Free access

Research article

First published 2013-3

Mrp1 is Essential for Sphingolipid Signaling to P-Glycoprotein in Mouse Blood–Brain and Blood–Spinal Cord Barriers

Tara A Cartwright, Christopher R Campos, Ronald E Cannon [...]

Journal of Cerebral Blood Flow & Metabolism

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