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Research article

First published 2025-9

Distinct glial functions are associated with Alzheimer's disease based on cell-type- and pathway-specific polygenic risk score analysis

Tyrell Pratt, Alice Lee, Jennifer Zheng [...]

Journal of Alzheimer’s Disease

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Research article

First published 2023-09-26

Pathway-Specific Polygenic Risk Scores Correlate with Clinical Status and Alzheimer’s Disease-Related Biomarkers

Nicholas J. Schork, Jeremy A. Elman, for the Alzheimer’s Disease Neuroimaging Initiative

Journal of Alzheimer’s Disease

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Research article

First published 2022-02-15

A Pathway-Specific Polygenic Risk Score Is Associated with Tau Pathology and Cognitive Decline

Yuqing Sun, Meng Wang, Yuxin Zhao [...]

Journal of Alzheimer’s Disease

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Research article

First published 2016-11-19

Pathway-Specific Polygenic Risk Scores as Predictors of Amyloid-β Deposition and Cognitive Function in a Sample at Increased Risk for Alzheimer’s Disease

Burcu F. Darst, Rebecca L. Koscik, Annie M. Racine [...]

Journal of Alzheimer’s Disease

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Research article

First published 2023-08-15

Effect of Pathway-Specific Polygenic Risk Scores for Alzheimer’s Disease (AD) on Rate of Change in Cognitive Function and AD-Related Biomarkers Among Asymptomatic Individuals

Yuexuan Xu, Eva Vasiljevic, Yuetiva K. Deming [...]

Journal of Alzheimer’s Disease

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Research article

First published 2021-01-05

The Differential Influence of Immune,Endocytotic,and Lipid Metabolism Genes on Amyloid Deposition and Neurodegeneration in Subjects at Risk of Alzheimer’s Disease

Grazia Daniela Femminella, Denise Harold, James Scott [...]

Journal of Alzheimer’s Disease

Open access

Research article

First published 2020-04-21

From Polygenic Scores to Precision Medicine in Alzheimer’s Disease: A Systematic Review

Judith R. Harrison, Sumit Mistry, Natalie Muskett [...]

Journal of Alzheimer’s Disease

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Research article

First published 2024-06-11

Epistatic Features and Machine Learning Improve Alzheimer’s Disease Risk Prediction Over Polygenic Risk Scores

Stephen Hermes, Janet Cady, Steven Armentrout [...]

Journal of Alzheimer’s Disease

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Research article

First published 2023-01-31

Novel Genetic Variants in TP37,PIK3R1,CALM1,and PLCG2 of the Neurotrophin Signaling Pathway Are Associated with the Progression from Mild Cognitive Impairment to Alzheimer’s Disease

Huiyue Li, Hongliang Liu, Michael W. Lutz [...]

Journal of Alzheimer’s Disease

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Research article

First published 2022-10

Shared genetic background between SARS-CoV-2 infection and large artery stroke

Livia Parodi, Evangelos Pavlos Myserlis, Jaeyoon Chung [...]

International Journal of Stroke

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