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Research article

First published 2015-4

Bayesian Optimal Interval Design for Phase I Oncology Clinical Trials

Bryan M. Fellman, Ying Yuan

The Stata Journal: Promoting communications on statistics and Stata

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Research article

First published 2019-11

Optimal designs for testing hypothesis in multiarm clinical trials

Alessandro Baldi Antognini, Marco Novelli, Maroussa Zagoraiou

Statistical Methods in Medical Research

Open access

Research article

First published 2025-8

Nature-inspired metaheuristics for optimizing dose-finding and computationally challenging clinical trial designs

Weng Kee Wong, Yevgen Ryeznik, Oleksandr Sverdlov [...]

Clinical Trials

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Research article

First published 2024-6

Adaptive phase I–II clinical trial designs identifying optimal biological doses for targeted agents and immunotherapies

Yong Zang, Beibei Guo, Yingjie Qiu [...]

Clinical Trials

Open access

Research article

First published 2025-11

A robust Bayesian dose optimization design with backfill and randomization for phase I/II clinical trials

Yingjie Qiu, Mingyue Li

Statistical Methods in Medical Research

Open access

Research article

First published 2016-6

Decision-theoretic designs for small trials and pilot studies: A review

Siew Wan Hee, Thomas Hamborg, Simon Day [...]

Statistical Methods in Medical Research

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Research article

First published 2018-1

Optimal two-stage enrichment design correcting for biomarker misclassification

Yong Zang, Beibei Guo

Statistical Methods in Medical Research

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Research article

First published 2017-1

Methodological Extensions of Phase 2 Trial Designs Based on Program-Level Considerations

James Bolognese, Jaydeep Bhattacharyya, Chris Assaid [...]

Therapeutic Innovation & Regulatory Science

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Research article

First published 2018-4

Sequential designs with small samples: Evaluation and recommendations for normal responses

Stavros Nikolakopoulos, Kit CB Roes, Ingeborg van der Tweel

Statistical Methods in Medical Research

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Research article

First published 2007-12

Optimal designs for clinical trials with second-order polynomial treatment effects

Bjorn Winkens, Hubert J. A. Schouten, Gerard J. P. van Breukelen [...]

Statistical Methods in Medical Research

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