Sage Journals: Discover world-class research

Open access

Research article

First published 2012-1

Stimulation of Peripheral Kappa Opioid Receptors Inhibits Inflammatory Hyperalgesia via Activation of the PI3Kγ/AKT/nNOS/NO Signaling Pathway

Thiago M Cunha, Guilherme R Souza, Andressa C Domingues [...]

Molecular Pain

Open access

Review article

First published 2012-1

Molecular and Cellular Mechanisms of the Age-Dependency of Opioid Analgesia and Tolerance

Jing Zhao, Xin Xin, Guo-Xi Xie [...]

Molecular Pain

Open access

Research article

First published 2025

Exploring novel non-opioid pathways and therapeutics for pain modulation

Isabella Alessi, Kaysie L Banton, Sliter J [...]

Molecular Pain

Retricted access

Research article

First published 1991-11

The Role of Endogenous Opioids and Their Receptors in the Immune System

Daniel J. J. Carr

Experimental Biology and Medicine

Open access

Research article

First published 2017

Usefulness for the combination of G protein- and β-arrestin-biased ligands of μ-opioid receptors: Prevention of antinociceptive tolerance

Tomohisa Mori, Naoko Kuzumaki, Takamichi Arima [...]

Molecular Pain

Open access

Review article

First published 2022-12

The Interplay between Chronic Pain,Opioids,and the Immune System

Valentina Malafoglia, Sara Ilari, Laura Vitiello [...]

The Neuroscientist

Open access

Review article

First published 2007-1

Trafficking of Central Opioid Receptors and Descending Pain Inhibition

Bihua Bie, Zhizhong Z Pan

Molecular Pain

Retricted access

Research article

First published 2019-10

Pharmacology Update: Low-Dose Naltrexone as a Possible Nonopioid Modality for Some Chronic,Nonmalignant Pain Syndromes

Diana Trofimovitch, Steven J. Baumrucker

American Journal of Hospice and Palliative Medicine®

Open access

Research article

First published 2011-06

NO-released Zinc Supports the Simultaneous Binding of Raf-1 and PKCγ Cysteine-Rich Domains to HINT1 Protein at the Mu-Opioid Receptor

María Rodríguez-Muñoz, Elena de la Torre-Madrid, Pilar Sánchez-Blázquez [...]

Antioxidants & Redox Signaling

Free access

Research article

First published 2012-6

Adenosine and Opioid Receptors Do Not Trigger the Cardioprotective Effect of Mild Hypothermia

Lys Darbera, Mourad Chenoune, Fanny Lidouren [...]

Journal of Cardiovascular Pharmacology and Therapeutics

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