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Articles (205)

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1-10 of 205 results for nonclinical toxicity.

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Select article: Appropriate Use of Recovery Groups in Nonclinical Toxicity Studies: Value in a Science-Driven Case-by-Case Approach

Free access

Research article

First published 2012-3

Appropriate Use of Recovery Groups in Nonclinical Toxicity Studies: Value in a Science-Driven Case-by-Case Approach

K. Pandher, M. W. Leach, L. A. Burns-Naas

Veterinary Pathology

Select article: STP Town Hall Discussion on the Use of Virtual Control Groups in Nonclinical Toxicity Studies

Retricted access

Meeting report

First published 2025-12

STP Town Hall Discussion on the Use of Virtual Control Groups in Nonclinical Toxicity Studies

Kirstin Barnhart, Brad Bolon, Laura Boone [...]

Toxicologic Pathology

Select article: Opinion on the Optimal Histologic Evaluation of the Bone Marrow in Nonclinical Toxicity Studies

Free access

Research article

First published 2022-2

Opinion on the Optimal Histologic Evaluation of the Bone Marrow in Nonclinical Toxicity Studies

Kathleen E. Biddle

Toxicologic Pathology

Select article: Clinical Pathology Testing Recommendations for Nonclinical Toxicity and Safety Studies

Free access

Research article

First published 1992-5

Clinical Pathology Testing Recommendations for Nonclinical Toxicity and Safety Studies

Kurt Weingand, John Bloom, Michael Carakostas [...]

Toxicologic Pathology

Select article: Community Opinions on the Collection and Use of Historical Control Data in Nonclinical Toxicity Studies

Retricted access

Research article

First published 2016-3

Community Opinions on the Collection and Use of Historical Control Data in Nonclinical Toxicity Studies

Lauren Murphree Mihalcik, Megan Bausman, Paul Brown [...]

Therapeutic Innovation & Regulatory Science

Select article: An Overview of Nonclinical and Clinical Liver Toxicity Associated With AAV Gene Therapy

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Meeting report

First published 2023-10

An Overview of Nonclinical and Clinical Liver Toxicity Associated With AAV Gene Therapy

Laurence O. Whiteley

Toxicologic Pathology

Select article: Toxicologic Pathology Forum*: Opinion on Qualitative Severity Descriptors to Express Magnitude of Changes in Clinical Pathology Endpoints in Nonclinical Toxicity Studies

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Research article

First published 2025-8

Toxicologic Pathology Forum*: Opinion on Qualitative Severity Descriptors to Express Magnitude of Changes in Clinical Pathology Endpoints in Nonclinical Toxicity Studies

N. K. Tripathi, L. Ramaiah, T. Arndt [...]

Toxicologic Pathology

Select article: Toxicologic Pathology Forum: Tissue Evaluation in Nonclinical Toxicity Studies for Prophylactic Vaccines

Open access

Research article

First published 2023-1

Toxicologic Pathology Forum: Tissue Evaluation in Nonclinical Toxicity Studies for Prophylactic Vaccines

Rani S. Sellers

Toxicologic Pathology

Select article: Compilation of International Regulatory Guidance Documents for Neuropathology Assessment During Nonclinical General Toxicity and Specialized Neurotoxicity Studies

Free access

Research article

First published 2011-1

Compilation of International Regulatory Guidance Documents for Neuropathology Assessment During Nonclinical General Toxicity and Specialized Neurotoxicity Studies

Brad Bolon, Alys Bradley, Mark Butt [...]

Toxicologic Pathology

Select article: Predictivity/Translatability of Toxicities Observed in Nonclinical Toxicology Studies to Clinical Safety Outcomes in Drug Development: Case Examples

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Research article

First published 2020-3

Predictivity/Translatability of Toxicities Observed in Nonclinical Toxicology Studies to Clinical Safety Outcomes in Drug Development: Case Examples

Nicola J. Stagg, Hanan N. Ghantous, Robert Roth [...]

International Journal of Toxicology

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