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Articles (42)

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1-10 of 42 results for non-rodent toxicity studies

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Select article: Regulatory Forum Opinion Piece: Obligatory Microscopic Examination of Intermediate Dose Groups in Non-Rodent Toxicity Studies—Is It Necessary?

Free access

Research article

First published 2012-7

Regulatory Forum Opinion Piece: Obligatory Microscopic Examination of Intermediate Dose Groups in Non-Rodent Toxicity Studies—Is It Necessary?

Diann L. Weddle, Charles R. Mahrt, Stephen P. Schmidt

Toxicologic Pathology

Select article: Scientific and Regulatory Policy Committee Points to Consider* for Determining and Reporting Cause of Death/Moribundity in Non-Rodent Species in Toxicity Studies

Retricted access

Research article

First published 2025-7

Scientific and Regulatory Policy Committee Points to Consider* for Determining and Reporting Cause of Death/Moribundity in Non-Rodent Species in Toxicity Studies

Karyn Colman, Kathleen A. Funk, Michael Boyle [...]

Toxicologic Pathology

Select article: Evaluation of Organ Weights for Rodent and Non-Rodent Toxicity Studies: A Review of Regulatory Guidelines and a Survey of Current Practices

Free access

Research article

First published 2007-8

Evaluation of Organ Weights for Rodent and Non-Rodent Toxicity Studies: A Review of Regulatory Guidelines and a Survey of Current Practices

Bindhu Michael, Barry Yano, Rani S. Sellers [...]

Toxicologic Pathology

Select article: Exploring the Definition of “Similar Toxicities”: Case Studies Illustrating Industry and Regulatory Interpretation of ICH S6(R1) for Long-Term Toxicity Studies in One or Two Species

Open access

Review article

First published 2022-5

Exploring the Definition of “Similar Toxicities”: Case Studies Illustrating Industry and Regulatory Interpretation of ICH S6(R1) for Long-Term Toxicity Studies in One or Two Species

Helen Prior, David O Clarke, David Jones [...]

International Journal of Toxicology

Select article: Chemistry and Safety of Triclosan,and Its Use as an Antimicrobial Coating on Coated VICRYL* Plus Antibacterial Suture (Coated Polyglactin 910 Suture with Triclosan)

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Research article

First published 2002-12

Chemistry and Safety of Triclosan,and Its Use as an Antimicrobial Coating on Coated VICRYL* Plus Antibacterial Suture (Coated Polyglactin 910 Suture with Triclosan)

Thomas A. Barbolt

Surgical Infections

Select article: Prospects for reducing and refining the use of dogs in the regulatory toxicity testing of pharmaceuticals

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Research article

First published 2000-08

Prospects for reducing and refining the use of dogs in the regulatory toxicity testing of pharmaceuticals

C L Broadhead, G Betton, R Combes [...]

Human & Experimental Toxicology

Select article: Single- and repeat-dose toxicity of IDX14184,a nucleotide prodrug with antiviral activity for hepatitis C viral infection,in mice,rats,and monkeys

Free access

Research article

First published 2016-5

Single- and repeat-dose toxicity of IDX14184,a nucleotide prodrug with antiviral activity for hepatitis C viral infection,in mice,rats,and monkeys

S Luo, R Rush, D Standring

Human & Experimental Toxicology

Select article: Rodent Aβ(1–42) exhibits oxidative stress properties similar to those of human Aβ(1–42): Implications for proposed mechanisms of toxicity

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Research article

First published 2004

Rodent Aβ(1–42) exhibits oxidative stress properties similar to those of human Aβ(1–42): Implications for proposed mechanisms of toxicity

Debra Boyd-Kimball, Rukhsana Sultana, Hafiz Mohmmad-Abdul [...]

Journal of Alzheimer’s Disease

Select article: Calcium gluconate and sodium succinate for therapy of sodium fluoroacetate experimental intoxication in cats: clinical and electrocardiographic evaluation

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Research article

First published 2006-04

Calcium gluconate and sodium succinate for therapy of sodium fluoroacetate experimental intoxication in cats: clinical and electrocardiographic evaluation

R C Collicchio-Zuanaze, M Sakate, D S Schwartz [...]

Human & Experimental Toxicology

Select article: The Integrated Acute Systemic Toxicity Project (ACuteTox) for the Optimisation and Validation of Alternative In Vitro Tests

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Research article

First published 2007-3

The Integrated Acute Systemic Toxicity Project (ACuteTox) for the Optimisation and Validation of Alternative In Vitro Tests

Cecilia Clemedson, Ada Kolman, Anna Forsby

Alternatives to Laboratory Animals

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