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Research article

First published 2008-10

High-Throughput Microsomal Stability Assay for Screening New Chemical Entities in Drug Discovery

Massimiliano Fonsi, Maria V. Orsale, Edith Monteagudo

Journal of Biomolecular Screening

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Other

First published 2003-08

Optimization of a Higher Throughput Microsomal Stability Screening Assay for Profiling Drug Discovery Candidates

Li Di, Edward H. Kerns, Yan Hong [...]

Journal of Biomolecular Screening

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Research article

First published 2021-12

Validating ADME QSAR Models Using Marketed Drugs

Vishal Siramshetty, Jordan Williams, Ðắc-Trung Nguyễn [...]

Journal of Biomolecular Screening

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Research article

First published 2018-8

A reliable and stable method for the determination of foretinib in human plasma by LC-MS/MS: Application to metabolic stability investigation and excretion rate

Mohamed W Attwa, Adnan A Kadi, Hany W Darwish [...]

European Journal of Mass Spectrometry

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News

First published 1986-1

Rat Microsomes and Cytosol Immobilized by Microencapsulation in Artificial Cells

Z.Y. Yuan, T.M.S. Chang

The International Journal of Artificial Organs

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Research article

First published 1972-5

Liver Microsomal Glucose-6-phosphatase: Protection by Inhibitors and Substrates Against Thermal Inactivation 1

Su-Mei Huang, Robert C. Nordlie

Experimental Biology and Medicine

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Research article

First published 1970-10

Lipid Composition of Tissues from Electrophorus electricus

Eberhard G. Trams, Charles P. Hoiberg

Experimental Biology and Medicine

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Research article

First published 1988-12

Genetically Engineered Modification of P450 Monooxygenases: Functional Analysis of the Amino-Terminal Hydrophobic Region and Hinge Region of the P450/Reductase Fused Enzyme

Yoshiyasu Yabusaki, Hiroko Murakami, Toshiyuki Sakaki [...]

DNA and Cell Biology

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Research article

First published 2008-02

An Automated Liquid Chromatography-Mass Spectrometry Process to Determine Metabolic Stability Half-Life and Intrinsic Clearance of Drug Candidates by Substrate Depletion

Colleen A. McNaney, Dieter M. Drexler, Serhiy Y. Hnatyshyn [...]

ASSAY and Drug Development Technologies

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Research article

First published 2007-04

An Automated High Throughput Liquid Chromatography–Mass Spectrometry Process to Assess the Metabolic Stability of Drug Candidates

Dieter M. Drexler, James V. Belcastro, Kenneth E. Dickinson [...]

ASSAY and Drug Development Technologies

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