Sage Journals: Discover world-class research

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Research article

First published 2015-10

The Antipancreatic Cancer Activity of OSI-027,a Potent and Selective Inhibitor of mTORC1 and mTORC2

Bo Chen, Ming Xu, Hui Zhang [...]

DNA and Cell Biology

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Research article

First published 2009-10

High-Throughput Screening for mTORC1/mTORC2 Kinase Inhibitors Using a Chemiluminescence-Based ELISA Assay

Shripad V. Bhagwat, Jennifer Kahler, Yan Yao [...]

ASSAY and Drug Development Technologies

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Research article

First published 2020-8

mTORC1-IRE1α pathway activation contributes to palmitate-elicited triglyceride secretion and cell death in hepatocytes

Jun Wang, Yingli Chen, Qing Song [...]

Experimental Biology and Medicine

Open access

Review article

First published 2021

MTORC1 signaling as a biomarker in major depressive disorder and its pharmacological modulation by novel rapid-acting antidepressants

Tomasz Cholewinski, Diana Pereira, Matthijs Moerland [...]

Therapeutic Advances in Psychopharmacology

Free access

Research article

First published 2021-5

TRIP13 promotes lung cancer cell growth and metastasis through AKT/mTORC1/c-Myc signaling

Weiyang Cai, Wei Ni, Yin Jin [...]

Cancer Biomarkers

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Research article

First published 2016-01

Beneficial Effects of Early mTORC1 Inhibition after Traumatic Brain Injury

Ina Nikolaeva, Beth Crowell, Julia Valenziano [...]

Journal of Neurotrauma

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Research article

First published 2015-01

Genetic Activation of mTORC1 Signaling Worsens Neurocognitive Outcome after Traumatic Brain Injury

Natalia S. Rozas, John B. Redell, Julia L. Hill [...]

Journal of Neurotrauma

Open access

Article commentary

First published 2020-3

mTORC2 Steals the Spotlight

Laura A. Jansen

Epilepsy Currents

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Research article

First published 2024-08

Defining the In Vivo Role of mTORC1 in Thyrocytes by Studying the TSC2 Conditional Knockout Mouse Model

Camila Ludke Rossetti, Bruna Lourençoni Alves, Flavia Leticia Martins Peçanha [...]

Thyroid®

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Research article

First published 2020-6

Valsartan ameliorates high glucose-induced peritoneal ﬁbrosis by blocking mTORC1 signaling

Jing Liu, Yuan Feng, Cheng Sun [...]

Experimental Biology and Medicine

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