Sage Journals: Discover world-class research

Retricted access

Research article

First published 2025-8

First-in-human trial of Center Wire for neuroendovascular therapy to avoid guidewire-related complications

Shirabe Matsumoto, Hirotoshi Imamura, Ariel Takayanagi [...]

Interventional Neuroradiology

Retricted access

Research article

First published 2019

Shared Learnings on the New EMA First-in-Human and Early Clinical Trial Guideline: Proceedings From a DIAlogue Session at DIA Europe 2018

Jan Willem van der Laan, Charles T. Benson, Walter Janssens [...]

Therapeutic Innovation & Regulatory Science

Open access

Research article

First published 2025

Rationale and design of the CORDIAL first-in-human clinical trial: A system for sorbent-assisted continuous flow peritoneal dialysis

Joost Christiaan de Vries, Maaike K van Gelder, Dian P Bolhuis [...]

Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis

Retricted access

Other

First published 2001-10

Optimizing First-Time-in-Human Trial Design for Studying Dose Proportionality

Yin Yin, Chao Chen

Therapeutic Innovation & Regulatory Science

Retricted access

Research article

First published 2026-1

First-in-human gene therapy clinical trials in the media: Exploring patient narratives

Rachele E. Willard, Marilyn S. Baffoe-Bonnie, Hasmin C. Ramirez [...]

Public Understanding of Science

Open access

Research article

First published 2017

Challenges to Informed Consent in First-In-Human Trials Involving Novel Treatments: A Case Study of Parkinson’s Disease

Kristina Hug, Mats Johansson

Journal of Parkinson’s Disease

Open access

Research article

First published 2018

First Human Trial of High-Frequency Irreversible Electroporation Therapy for Prostate Cancer

Shoulong Dong, Haifeng Wang, Yajun Zhao [...]

Technology in Cancer Research & Treatment

Retricted access

Research article

First published 2025-10

First-in-Human Clinical Trial of the WeFlow-JAAA Endograft System in Patients With Juxtarenal Abdominal Aortic Aneurysms

Jiang-Ping Gao, Hong-Peng Zhang, Jiang Xiong [...]

Journal of Endovascular Therapy

Open access

Research article

First published 2023

First-in-human clinical trial of the NKT cell-stimulatory glycolipid OCH in multiple sclerosis

Wakiro Sato, Daisuke Noto, Manabu Araki [...]

Therapeutic Advances in Neurological Disorders

Open access

Research article

First published 2020

First-in-human phase I trial of anti-hepatocyte growth factor antibody (YYB101) in refractory solid tumor patients

Seung Tae Kim, Jung Yong Hong, Se Hoon Park [...]

Therapeutic Advances in Medical Oncology

Search results