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Research article

First published 2015-3

Nonparametric Estimation of Maximum Tolerated Dose (MTD) In The Context of Phase I Clinical Trials

Anup Dewanji, Gopal K. Basak, Atanu Biswas

Calcutta Statistical Association Bulletin

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Article commentary

First published 2017-7

Tg.rasH2 Mice and not CByB6F1 Mice Should Be Used for 28-Day Dose Range Finding Studies Prior to 26-Week Tg.rasH2 Carcinogenicity Studies

Madhav G. Paranjpe, Jessica Belich, Tom J. Vidmar [...]

International Journal of Toxicology

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Other

First published 2005-1

Development of Interactive Software for Bayesian Optimal Phase 1 Clinical Trial Design *

William F. Rosenberger, Gerald C. Canfield, Inna Perevozskaya [...]

Therapeutic Innovation & Regulatory Science

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Research article

First published 2022-2

Stopping rules for phase I clinical trials with dose expansion cohorts

Sean M Devlin, Alexia Iasonos, John O’Quigley

Statistical Methods in Medical Research

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Research article

First published 2018-11

Hierarchical models for sharing information across populations in phase I dose-escalation studies

Kristen M Cunanan, Joseph S Koopmeiners

Statistical Methods in Medical Research

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Research article

First published 2015-7

Regulatory Forum Commentary* Counterpoint

Jarig Darbes, Frank D. Sistare, Joseph J. DeGeorge

Toxicologic Pathology

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Research article

First published 2023-6

Backfilling cohorts in phase I dose-escalation studies

Helen Barnett, Oliver Boix, Dimitris Kontos [...]

Clinical Trials

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Research article

First published 2020-2

An adaptive design for the identification of the optimal dose using joint modeling of continuous repeated biomarker measurements and time-to-toxicity in phase I/II clinical trials in oncology

Maria-Athina Altzerinakou, Xavier Paoletti

Statistical Methods in Medical Research

Free access

Research article

First published 2011-12

Biodistribution,Toxicology,and Radiation Dosimetry of 5-HT 1A -Receptor Agonist Positron Emission Tomography Ligand [ 11 C]CUMI-101

Dileep J. S. Kumar, Bing Bai, Hanna H. Ng [...]

International Journal of Toxicology

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Research article

First published 2015-9

Evaluation of an Adaptive Maximizing Design Study Based on Clinical Utility Versus Morphine for TRV130 Proof-of-Concept and Dose-Regimen Finding in Patients With Postoperative Pain After Bunionectomy

James A. Bolognese, Ruth Ann Subach, Franck Skobieranda

Therapeutic Innovation & Regulatory Science

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