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Retricted access

Research article

First published 2001-10

Empty Capsids in Column-Purified Recombinant Adenovirus Preparations

Gary Vellekamp, Frederick W. Porter, Suganto Sutjipto [...]

Human Gene Therapy

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Research article

First published 2005-01

Characterization of Empty Capsids from a Conditionally Replicating Adenovirus for Gene Therapy

Suganto Sutjipto, Sundari Ravindran, Douglas Cornell [...]

Human Gene Therapy

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Research article

First published 2019-08

Analytical Strategies for Quantification of Adeno-Associated Virus Empty Capsids to Support Process Development

Xiaotong Fu, Wei-Chiang Chen, Christopher Argento [...]

Human Gene Therapy Methods (Part B)

Open access

Research article

First published 2023-01

Quantitation of Coxsackievirus A21 Viral Proteins in Mixtures of Empty and Full Capsids Using Capillary Western

Paul F. Gillespie, Richard R. Rustandi, Andrew R. Swartz [...]

Human Gene Therapy

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Review article

First published 2017-02

Empty Capsids and Macrophage Inhibition/Depletion Increase rAAV Transgene Expression in Joints of Both Healthy and Arthritic Mice

Caroline J. Aalbers, Niels Broekstra, Mariska van Geldorp [...]

Human Gene Therapy

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Research article

First published 2022-02

Size Exclusion Chromatography with Dual Wavelength Detection as a Sensitive and Accurate Method for Determining the Empty and Full Capsids of Recombinant Adeno-Associated Viral Vectors

He Meng, Michelle Sorrentino, Denise Woodcock [...]

Human Gene Therapy

Open access

Research article

First published 2022-07

Reverse-Phase Ultra-Performance Chromatography Method for Oncolytic Coxsackievirus Viral Protein Separation and Empty to Full Capsid Quantification

James Z. Deng, Richard R. Rustandi, Damon Barbacci [...]

Human Gene Therapy

Open access

Research article

First published 2021-11

Development and Validation of an Anion Exchange High-Performance Liquid Chromatography Method for Analysis of Empty Capsids and Capsids Encapsidating Genetic Material in a Purified Preparation of Recombinant Adeno-Associated Virus Serotype 5

Pranav R.H. Joshi, Alice Bernier, Parminder S. Chahal [...]

Human Gene Therapy

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Research article

First published 2026-4

Exploring Development Options of a Polishing Chromatography Step for AAV7 and AAV8

Xiaotong Fu, Colin Haws, Darren Begley [...]

Human Gene Therapy

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Editorial

First published 2017-02

Empty Adeno-Associated Virus Capsids: Contaminant or Natural Decoy?

Terence R. Flotte

Human Gene Therapy

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