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Open access

Research article

First published 2014-1

Efficacy versus Toxicity - The Ying and Yang in Translating Nanomedicines

Sahadev A Shankarappa, Manzoor Koyakutty, Shantikumar V Nair

Nanomaterials and Nanotechnology

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Research article

First published 2018-6

A correlation study of fluorouracil pharmacodynamics with clinical efficacy and toxicity

Ece Esin, Tugba Akin Telli, Deniz Yuce [...]

Tumori Journal

Open access

Research article

First published 2020-2

Association of MTHFR and RFC1 gene polymorphisms with methotrexate efficacy and toxicity in Chinese Han patients with rheumatoid arthritis

Shengli Wang, Shuguang Zuo, Zhigang Liu [...]

Journal of International Medical Research

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Research article

First published 2021-3

Probability intervals of toxicity and efficacy design for dose-finding clinical trials in oncology

Xiaolei Lin, Yuan Ji

Statistical Methods in Medical Research

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Research article

First published 2020-1

A latent variable model for improving inference in trials assessing the effect of dose on toxicity and composite efficacy endpoints

James MS Wason, Shaun R Seaman

Statistical Methods in Medical Research

Free access

Research article

First published 1999-01

Tumor Models: Assessing Toxicity in Efficacy Studies

Lawrence H. Arp

Toxicologic Pathology

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Research article

First published 2021-12

Influence of RFC1 c.80A>G Polymorphism on Methotrexate-Mediated Toxicity and Therapeutic Efficacy in Rheumatoid Arthritis: A Meta-analysis

Shaik Mohammad Naushad, Salman A. Alrokayan, Fahad N. Almajhdi [...]

Annals of Pharmacotherapy

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Research article

First published 2024-4

BOIN-ETC: A Bayesian optimal interval design considering efficacy and toxicity to identify the optimal dose combinations

Tomoyuki Kakizume, Kentaro Takeda, Masataka Taguri [...]

Statistical Methods in Medical Research

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Research article

First published 2014-2

A Bayesian adaptive Phase I–II clinical trial for evaluating efficacy and toxicity with delayed outcomes

Joseph S Koopmeiners, Jaime Modiano

Clinical Trials

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Research article

First published 1995-5

Efficacy and Toxicity of Amphotericin B Liposomal and Lipid Formulations

Jay P Rho, Jennifer H Cupo

Journal of Pharmacy Technology

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