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First published 2005-4

Choosing the Number of Doses and the Cohort Size for Phase 1 Dose-Escalation Studies

Yinghui Zhou

Therapeutic Innovation & Regulatory Science

Open access

Research article

First published 2008-10

Summary of Dose-Response Modeling for Developmental Toxicity Studies

Daniel L. Hunt, Shesh N. Rai, Chin-Shang Li

Dose-Response

Retricted access

Research article

First published 2012-4

Low-Dose Brain Computer Tomography Sensitivity: A Comparative Study with a Conventional Technique

I. Aprile, I. Ottaviano, E. Buono [...]

The Neuroradiology Journal

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Research article

First published 2009-07

Docetaxel and Gemcitabine in the Treatment of Metastatic Breast Carcinoma: A Dose Finding Study

Vita Leonardi, Valentina Palmisano, Alessio Pepe [...]

Tumori Journal

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Other

First published 2005-4

The Expected Toxicity Rate at the Maximum Tolerated Dose in Bridging Studies in Alzheimer's Disease

Seung-Ho Kang, Chul Ahn

Therapeutic Innovation & Regulatory Science

Free access

Article commentary

First published 2017-7

Tg.rasH2 Mice and not CByB6F1 Mice Should Be Used for 28-Day Dose Range Finding Studies Prior to 26-Week Tg.rasH2 Carcinogenicity Studies

Madhav G. Paranjpe, Jessica Belich, Tom J. Vidmar [...]

International Journal of Toxicology

Free access

Research article

First published 2012-7

Regulatory Forum Opinion Piece: Obligatory Microscopic Examination of Intermediate Dose Groups in Non-Rodent Toxicity Studies—Is It Necessary?

Diann L. Weddle, Charles R. Mahrt, Stephen P. Schmidt

Toxicologic Pathology

Open access

Research article

First published 2020-4

Designing and evaluating dose-escalation studies made easy: The MoDEsT web app

Philip Pallmann, Fang Wan, Adrian P Mander [...]

Clinical Trials

Free access

Research article

First published 1995-02

A Systemic Exposure-Based Alternative to the Maximum Tolerated Dose for Carcinogenicity Studies of Human Therapeutics

Joseph F. Contrera, Abigail C. Jacobs, Hullahalli R. Prasanna [...]

International Journal of Toxicology

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Research article

First published 1993-5

A Dosing Study of Nonoxynol-9 and Genital Irritation

R E Roddy, M Cordero, C Cordero [...]

International Journal of STD & AIDS

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